Difference between revisions of "User:Z3289738"

From Embryology
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'''Q1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique and add a correctly formatted link to the Nobel page.
 
'''Q1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique and add a correctly formatted link to the Nobel page.
 
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Robert G. Edwards, the physiologist who developed the In Vitro Fertilizationtreatment, was awarded the Nobel Prize in Physiology or Medicine in 2010. [http://www.nobelprize.org/nobel_prizes/medicine/laureates/2010/press.html/# Nobel Prize Page]
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'''Q2. Identify and add a PubMed reference link to a recent paper on fertilisation and describe its key findings (1-2 paragraphs).
 
'''Q2. Identify and add a PubMed reference link to a recent paper on fertilisation and describe its key findings (1-2 paragraphs).
 
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Revision as of 22:48, 31 July 2012

Lab Attendance

Lab 1: Z3289738 11:49, 25 July 2012 (EST)


Individual Assessments

Lab 1

Q1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique and add a correctly formatted link to the Nobel page.


Robert G. Edwards, the physiologist who developed the In Vitro Fertilizationtreatment, was awarded the Nobel Prize in Physiology or Medicine in 2010. Nobel Prize Page


Q2. Identify and add a PubMed reference link to a recent paper on fertilisation and describe its key findings (1-2 paragraphs). <pubmed> 22729284</pubmed>

This article looks into the process of embryo implantation. It demonstrates how the activation of the epithelial Na(+) channel triggers prostoglandin E(2) release,phosphorylation of teh transcription factor CREB and upregulation of cyclooxygenase 2, the enzyme required for prostaglandin production and implantation. They detected maximum Epithelial Na(+) channel activation at the time of implantation in mice, and that blocking or knocking down this channel in mice resulted in failure to implant. These results indicate the importance of the Epithelial Na(+) Channel in the process of implantation, and the consequences of defects such as miscarriage and low success rates in IVF.