Template talk:Genetic Terms

From Embryology
  • Netrin - roles in cell migration and neural axon guidance (secreted and GPI-anchored proteins). Secreted netrins can act either positively (attractive) or negatively (repulsive).
  • Neurotrophin - secreted proteins interact with membrane tyrosine kinase receptors.
  • Robo receptor - a member of the immunoglobulin superfamily.
  • Semaphorin - (Sem) 8 vertebrate classes (class 3 secreted, classes 4 - 6 are transmembrane proteins, class 7 are GPI-anchored proteins). Secreted semaphorins bind the neuropilins, while the transmembrane semaphorins interact with the plexus, and GPI-anchored semaphorins are thought to use integrins as their receptors.
  • Slit - Slit proteins signal through Roundabout (Robo) receptors and can mediate chemorepulsive events during development.

  • anaphase - (Greek, ana = up, again) Cell division term referring to the fourth mitosis stage, where the paired chromatids now separate and migrate to spindle poles. This is followed by telophase.
mitosis Phases: prophase - prometaphase - metaphase - anaphase - telophase

  • prometaphase - (Greek, pro = before) Cell division term referring to the second mitotic stage, when the nuclear envelope breaks down into vesicles. Microtubules then extend from the centrosomes at the spindle poles (ends) and reach the chromosomes. This is followed by metaphase.

  • prophase - (Greek, pro = before) Cell division term referring to the first mitotic stage, when the diffusely stained chromatin resolves into discrete chromosomes, each consisting of two chromatids joined together at the centromere.