Template talk:Mitochondrial Disorders Table

Mitochondrial DNA disorder	Description	Prevalence	Life expectancy/morbidity
Kearns–Sayre syndrome	Progressive blindness and blocked heart	Rare disease	Onset before 15
CPEO (chronic progressive external opthalmoplegia)	Progressive wastage of eyelids, eyes and sometimes facial muscles	Rare disease	Onset in young adulthood
Pearson syndrome	Anaemia, pancreatic failure, muscle wastage	Very rare (less than 100 worldwide)	Early death
MELAS (myopathy, encephalopathy, lactic acidosis and stroke)	Stroke like episodes; muscle spasm; early dementia	Rare disease	Death before 40
MERFF (myoclonic epilepsy and ragged-red fibres)	Epilepsy, hearing loss, lactic acidosis, short stature	1 in 400,000 across Europe	Childhood onset
NARP (neurogenic weakness, ataxia and retinitis pigmentosa)	Muscle weakness, vision loss, learning disabilities	Rare disease	Onset in early childhood. Early death
MILS (maternally inherited Leigh syndrome)	Muscle weakness, heart and kidney failure, delayed development	Very rare	Onset in infancy. Death in early childhood
MIDD (maternally inherited diabetes and deafness)	Combination of all types of diabetes with deafness	Rare disease	Adult onset
LHON (Leber hereditary optic neuropathy)	Rapid blindness	1 in 30,000 across Europe	Range from early childhood to 70s
Myopathy and diabetes	Covers forms of muscular dystrophy		From infancy. Early death
Sensorineural hearing loss	Covers a range of hearing loss through to deafness	Common condition but rarely caused by mitochondrial disease	Onset at any age
Exercise intolerance	Range from lethargy to muscle wastage	1 in 8,000 but symptoms often combine with others	Onset in early life
Fatal infantile encephalopathy (Leigh syndrome)	Brain and nervous system dysfunctions	Very rare	Onset in infancy. Death in early childhood
Table based on Annex D, UK Mitochondrial Donation 2014.