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- 12:01, 3 October 2012 Z3332863 talk contribs uploaded File:Chemical physiological phenotype of nociceptors.JPG (The development of chemical and physiological phenotypes occurs via both intrinsic and extrinsic mechanisms. Intrinsically, nociceptors can express some level of neuropeptides such as Substance P (SP) and calcitonin gene-related peptide (CGRP). Contact wi)