File talk:Glomerular podocyte cartoon.jpg

Mesangial expansion: loss of some podocytes (20%) is associated with mesangial expansion possibly as an attempt to reduce the filtration surface area.

Adhesion formation: loss of podocytes resulting in appearance of bare areas of filtration surface results in adhesion of the bare surface to Bowman's capsule (synechia).

Segmental sclerosis: loss of podocytes beyond a critical level results in a fibrotic glomerular response in that part of the glomerulus (segmental sclerosis).

Global sclerosis: loss of podocytes beyond a critical level results in widespread scarring of that glomerulus (global sclerosis).

License Number

2712241111115

License date

Jul 18, 2011

Licensed content publisher

Nature Publishing Group

Licensed content publication

Kidney International

Licensed content title

The spectrum of podocytopathies: A unifying view of glomerular diseases

Licensed content author

R C Wiggins

Licensed content date

Apr 4, 2007

Volume number

71

Issue number

12

Type of Use

post on the internet

Requestor type

non-commercial (non-profit)

Format

electronic

Portion

figures/tables/illustrations

Number of figures/tables/illustrations

1

High-res required

no

Figures

Figure 2.Stages of glomerular development and progression with emphasis on the role of the podocyte

Author of this NPG article

no

Your reference number

Homepage URL for posting content

http://embryology.med.unsw.edu.au/embryology

Name of internet owner

Dr Mark Hill