File talk:Fetal temporomandibular joint 01.jpg

Anat Res Int. 2014;2014:732720. doi: 10.1155/2014/732720. Epub 2014 Jan 12. Analysis by Light, Scanning, and Transmission Microscopy of the Intima Synovial of the Temporomandibular Joint of Human Fetuses during the Development. Alvez CS1, Carvalho de Moraes LO2, Marques SR2, Tedesco RC2, Harb LJ3, Rodríguez-Vázquez JF4, Mérida-Velasco JR4, Alonso LG2. Author information Abstract Objective. To characterize morphologically and ultrastructurally using light microscopy, the scanning electron microscopy and transmission electron microscopy the intima synovial of the temporomandibular joint (TMJ) of human fetuses between the 10th and the 38th week of development. Materials and Methods. The TMJ was dissected bilaterally in 37 human fetuses belonging to the Institute of Embryology of the University Complutense of Madrid and of the Federal University of São Paulo. Results. The outcome by light microscopy showed the morphology of the TMJ and that the formation of inferior joint cavity precedes the superior joint cavity and the presence of blood vessels in the synovial. Conclusion. By scanning and transmission electron microscopy we observed the presence of two well-defined cell types in the intima layer of synovial of the TMJ of human fetuses, macrophage-like type A cell and fibroblast-like type B cell, and the presence of the a third cell type, defined by the name of intermediate lining cell in the intima layer of the synovial.

PMID 24527214

http://www.hindawi.com/journals/ari/2014/732720/

Figure 1: (a) human fetus (55 mm GL; 10th week of development). Frontal section. Hematoxylin-eosin. The inferior joint cavity is between the articular disc (D) and the mandibular condyle (C). Squamous part of the temporal bone (S); blood vessel (V); superficial temporal artery (TA). Bar = 1000 m. (b) Human fetus (95 mm GL; 12th week of development). Frontal section. Hematoxilyn-eosin. The superior and inferior joint cavities are visible. Articular disc (D). Blood vessel (V); squamous part of temporal bone (S); mandibular condyle (C); superficial temporal artery (TA). Bar = 2000 m. (c) Human fetus (125 mm GL; 14th week of development). Sagittal section. Hematoxilyn-eosin. Blood vessel (V) and blood cells (arrows) are visible at the synovial. Bar = 200 m. (d) human fetus (175 mm GL; 18th week of development). Sagittal section. Trichome Nylceo Marques de Castro. Section of the posterior region of the superior joint cavity. Blood vessel (V); lining cells are visible at the synovial (arrows). Bar = 200 m. (e) Human fetus (233 mm GL; 24th week of development). SEM (198). The inferior joint cavity on the fibrous portion (C) of the condyle, the articular disc (D), and the synovial (arrows) is observed. (f) Human fetus (300 mm GL; 32th week of development). SEM (920). Synovial lining cell (A) with a smooth surface formed by polygonal cells with clear limits (arrows). ( g) Human fetus (265-mm GL; 28th week of development). TEM (6000). Macrophage-like type A cell (M). ( h) Human fetus (285 mm GL; 30th week of development). TEM (3000). Fibroblast-like type B cell (F). (i) Human fetus (325 mm GL; 36th week of development). TEM (3000). The intima layer (IL) of synovial is been formed with intermediate lining cells (I) and macrophage-like type A cell (M). (j) Human fetus (335 mm GL; 38th week of development). TEM (3000). Intermediate lining cell (I) protruding in the intima layer of the synovial is visible.