File talk:Fetal length change.jpg

From Embryology

Mean organ weights of an Australian population of fetuses and infants

J Paediatr Child Health. 1990 Apr;26(2):101-3.

Cussen L, Scurry J, Mitropoulos G, McTigue C, Gross J. Source Department of Paediatrics, Monash Medical Centre, Clayton, Victoria, Australia.

Abstract

Charts of organ weights for an Australian population of fetuses and infants are presented. The organ-weight charts were compiled from 1337 stillbirths and liveborn babies whose gestational age ranged from 20 to 43 weeks, and who lived less than 72 h. Macerated stillbirths, multiple births and malformed organs were excluded. Pathological conditions aside from malformations were not excluded, leading to higher standard deviations compared with currently used charts. The organ weights are presented in two-week increments from 20 to 43 weeks' gestation as means, with standard deviations.

PMID: 2361065


Reference values for second trimester fetal and neonatal organ weights and measurements

Pediatr Dev Pathol. 2003 Mar-Apr;6(2):160-7. Epub 2003 Jan 29.

Hansen K, Sung CJ, Huang C, Pinar H, Singer DB, Oyer CE. Source Department of Pathology, Women and Infants Hospital of Rhode Island and Brown Medical School, 101 Dudley Street, Providence, RI 02905, USA.

Abstract

To establish accurate reference ranges for the entire second trimester, we documented organ weights, body weight, and linear measurements for 597 fetuses and neonates with gestational ages ranging from 12 to 26 wk. We determined the mean and standard deviation for weights and measurements at each week of gestation using the StatView trade mark SE + Graphics statistical program. The analyses revealed a linear correlation between the gestational age and, respectively, the toe-heel length, crown-rump length, and crown-heel length. Body and organ weights increase at varying rates throughout the second trimester. The data correlate well with weights and measurements previously published for the latter half of the second trimester, and extend these reference ranges to encompass the entire second trimester.

PMID 12548377

New Length Weight Table

Fetal Development - Length - Weight
Gestational age Fertilization age Length Mass
(LMP) (GA weeks) (weeks) (cm) (g)
8 (embryonic) 6 1.6 (crown to rump) 1
9 7 2.3 2
10 8 3.1 4
11 (fetal) 9 4.1 7
12 10 5.4 14
13 (second trimester) 11 7.4 23
14 12 8.7 43
15 13 10.1 70
16 14 11.6 100
17 15 13 140
18 16 14.2 190
19 17 15.3 240
20 18 16.4
25.6 (crown to heel)
300
21 19 26.7 360
22 20 27.8 430
23 21 28.9 501
24 22 30 600
25 23 34.6 660
26 24 35.6 760
27 25 36.6 875
28 (third trimester) 26 37.6 1005
29 27 38.6 1153
30 28 39.9 1319
31 29 41.1 1502
32 30 42.4 1702
33 31 43.7 1918
34 32 45 2146
35 33 46.2 2383
36 34 47.4 2622
37 35 48.6 2859
38 36 49.8 3083
39 37 50.7 3288
40 38 51.2 3462
41 39 51.7 3597
42 40 51.5 3685
References [1][2][3]

References

<pubmed>20121531</pubmed> <pubmed>9315150</pubmed> <pubmed>1732970</pubmed> <pubmed>5781799</pubmed>

Gestational Age

Gestational age (LMP)

(weeks)

Length (cm) Mass (g)
(crown to rump)
8 weeks 1.6 cm 1 gram
9 weeks 2.3 cm 2 grams
10 weeks 3.1 cm 4 grams
11 weeks 4.1 cm 7 grams
12 weeks 5.4 cm 14 grams
13 weeks 7.4 cm 23 grams
14 weeks 8.7 cm 43 grams
15 weeks 10.1 cm 70 grams
16 weeks 11.6 cm 100 grams
17 weeks 13 cm 140 grams
18 weeks 14.2 cm 190 grams
19 weeks 15.3 cm 240 grams
20 weeks 16.4 cm 300 grams
(crown to heel)
20 weeks 25.6 cm 300 grams
21 weeks 26.7 cm 360 grams
22 weeks 27.8 cm 430 grams
23 weeks 28.9 cm 501 grams
24 weeks 30 cm 600 grams
25 weeks 34.6 cm 660 grams
26 weeks 35.6 cm 760 grams
27 weeks 36.6 cm 875 grams
28 weeks 37.6 cm 1005 grams
29 weeks 38.6 cm 1153 grams
30 weeks 39.9 cm 1319 grams
31 weeks 41.1 cm 1502 grams
32 weeks 42.4 cm 1702 grams
33 weeks 43.7 cm 1918 grams
34 weeks 45 cm 2146 grams
5.25 pounds 46.2 cm 2383 grams
36 weeks 47.4 cm 2622 grams
37 weeks 48.6 cm 2859 grams
38 weeks 49.8 cm 3083 grams
39 weeks 50.7 cm 3288 grams
40 weeks 51.2 cm 3462 grams
41 weeks 51.7 cm 3597 grams
42 weeks 51.5 cm 3685 grams


Metric and USA

Gestational age (LMP) Length (US) Weight (US) Length (cm) Mass (g)
(crown to rump) (crown to rump)
8 weeks 0.63 inch 0.04 ounce 1.6 cm 1 gram
9 weeks 0.90 inch 0.07 ounce 2.3 cm 2 grams
10 weeks 1.22 inch 0.14 ounce 3.1 cm 4 grams
11 weeks 1.61 inch 0.25 ounce 4.1 cm 7 grams
12 weeks 2.13 inches 0.49 ounce 5.4 cm 14 grams
13 weeks 2.91 inches 0.81 ounce 7.4 cm 23 grams
14 weeks 3.42 inches 1.52 ounce 8.7 cm 43 grams
15 weeks 3.98 inches 2.47 ounces 10.1 cm 70 grams
16 weeks 4.57 inches 3.53 ounces 11.6 cm 100 grams
17 weeks 5.12 inches 4.94 ounces 13 cm 140 grams
18 weeks 5.59 inches 6.70 ounces 14.2 cm 190 grams
19 weeks 6.02 inches 8.47 ounces 15.3 cm 240 grams
20 weeks 6.46 inches 10.58 ounces 16.4 cm 300 grams
(crown to heel) (crown to heel)
20 weeks 10.08 inches 10.58 ounces 25.6 cm 300 grams
21 weeks 10.51 inches 12.70 ounces 26.7 cm 360 grams
22 weeks 10.94 inches 15.17 ounces 27.8 cm 430 grams
23 weeks 11.38 inches 1.10 pound 28.9 cm 501 grams
24 weeks 11.81 inches 1.32 pound 30 cm 600 grams
25 weeks 13.62 inches 1.46 pound 34.6 cm 660 grams
26 weeks 14.02 inches 1.68 pound 35.6 cm 760 grams
27 weeks 14.41 inches 1.93 pound 36.6 cm 875 grams
28 weeks 14.80 inches 2.22 pounds 37.6 cm 1005 grams
29 weeks 15.2 inches 2.54 pounds 38.6 cm 1153 grams
30 weeks 15.71 inches 2.91 pounds 39.9 cm 1319 grams
31 weeks 16.18 inches 3.31 pounds 41.1 cm 1502 grams
32 weeks 16.69 inches 3.75 pounds 42.4 cm 1702 grams
33 weeks 17.20 inches 4.23 pounds 43.7 cm 1918 grams
34 weeks 17.72 inches 4.73 pounds 45 cm 2146 grams
35 weeks 18.19 inches 5.25 pounds 46.2 cm 2383 grams
36 weeks 18.66 inches 5.78 pounds 47.4 cm 2622 grams
37 weeks 19.13 inches 6.30 pounds 48.6 cm 2859 grams
38 weeks 19.61 inches 6.80 pounds 49.8 cm 3083 grams
39 weeks 19.96 inches 7.25 pounds 50.7 cm 3288 grams
40 weeks 20.16 inches 7.63 pounds 51.2 cm 3462 grams
41 weeks 20.35 inches 7.93 pounds 51.7 cm 3597 grams
42 weeks 20.28 inches 8.12 pounds 51.5 cm 3685 grams


Predicted Menstrual Age (Weeks) From Crl Measurements (Cm)

CRL MA
0.2 5.7
2.2 8.9
4.2 11.1
6.2 12.6
8.2 14.2
10.2 16.1
0.3 5.9
2.3 9.0
4.3 11.2
6.3 12.7
8.3 14.2
10.3 16.2
0.4 6.1
2.4 9.1
4.4 11.2
6.4 12.8
8.4 14.3
10.4 16.3
0.5 6.2
2.5 9.2
4.5 11.3
6.5 12.8
8.5 14.4
10.5 16.4
0.6 6.4
2.6 9.4
4.6 11.4
6.6 12.9
8.6 14.5
10.6 16.5
0.7 6.6
2.7 9.5
4.7 11.5
6.7 13.0
8.7 14.6
10.7 16.6
0.8 6.7
2.8 9.6
4.8 11.6
6.8 13.1
8.8 14.7
10.8 16.7
0.9 6.9
2.9 9.7
4.9 11.7
6.9 13.1
8.9 14.8
10.9 16.8
1.0 7.2
3.0 9.9
5.0 11.7
7.0 13.2
9.0 14.9
11.0 16.9
1.1 7.2
3.1 10.0
5.1 11.8
7.1 13.3
9.1 15.0
11.1 17.0
1.2 7.4
3.2 10.1
5.2 11.9
7.2 13.4
9.2 15.1
11.2 17.1
1.3 7.5
3.3 10.2
5.3 12.0
7.3 13.4
9.3 15.2
11.3 17.2
1.4 7.7
3.4 10.3
5.4 12.0
7.4 13.5
9.4 15.3
11.4 17.3
1.5 7.9
3.5 10.4
5.5 12.1
7.5 13.6
9.5 15.3
11.5 17.4
1.6 8.0
3.6 10.5
5.6 12.2
7.6 13.7
9.6 15.4
11.6 17.5
1.7 8.1
3.7 10.6
5.7 12.3
7.7 13.8
9.7 15.5
11.7 17.6
1.8 8.3
3.8 10.7
5.8 12.3
7.8 13.8
9.8 15.6
11.8 17.7
1.9 8.4
3.9 10.8
5.9 12.4
7.9 13.9
9.9 15.7
11.9 17.8
2.0 8.6
4.0 10.9
6.0 12.5
8.0 14.0
10.0 15.9
12.0 17.9
2.1 8.7
4.1 11.0
6.1 12.6
8.1 14.1
10.1 16.0
12.1 18.0

non Sort

CRL MA
0.2 5.7
0.3 5.9
0.4 6.1
0.5 6.2
0.6 6.4
0.7 6.6
0.8 6.7
0.9 6.9
1.0 7.2
1.1 7.2
1.2 7.4
1.3 7.5
1.4 7.7
1.5 7.9
1.6 8.0
1.7 8.1
1.8 8.3
1.9 8.4
2.0 8.6
2.1 8.7
2.2 8.9
2.3 9.0
2.4 9.1
2.5 9.2
2.6 9.4
2.7 9.5
2.8 9.6
2.9 9.7
3.0 9.9
3.1 10.0
3.2 10.1
3.3 10.2
3.4 10.3
3.5 10.4
3.6 10.5
3.7 10.6
3.8 10.7
3.9 10.8
4.0 10.9
4.1 11.0
4.2 11.1
4.3 11.2
4.4 11.2
4.5 11.3
4.6 11.4
4.7 11.5
4.8 11.6
4.9 11.7
5.0 11.7
5.1 11.8
5.2 11.9
5.3 12.0
5.4 12.0
5.5 12.1
5.6 12.2
5.7 12.3
5.8 12.3
5.9 12.4
6.0 12.5
6.1 12.6
6.2 12.6
6.3 12.7
6.4 12.8
6.5 12.8
6.6 12.9
6.7 13.0
6.8 13.1
6.9 13.1
7.0 13.2
7.1 13.3
7.2 13.4
7.3 13.4
7.4 13.5
7.5 13.6
7.6 13.7
7.7 13.8
7.8 13.8
7.9 13.9
8.0 14.0
8.1 14.1
8.2 14.2
8.3 14.2
8.4 14.3
8.5 14.4
8.6 14.5
8.7 14.6
8.8 14.7
8.9 14.8
9.0 14.9
9.1 15.0
9.2 15.1
9.3 15.2
9.4 15.3
9.5 15.3
9.6 15.4
9.7 15.5
9.8 15.6
9.9 15.7
10.0 15.9
10.1 16.0
10.2 16.1
10.3 16.2
10.4 16.3
10.5 16.4
10.6 16.5
10.7 16.6
10.8 16.7
10.9 16.8
11.0 16.9
11.1 17.0
11.2 17.1
11.3 17.2
11.4 17.3
11.5 17.4
11.6 17.5
11.7 17.6
11.8 17.7
11.9 17.8
12.0 17.9
12.1 18.0
  • The 95% confidence interval is + 8% of the predicted age.

Radiology. 1992 Feb;182(2):501-5. Fetal crown-rump length: reevaluation of relation to menstrual age (5-18 weeks) with high-resolution real-time US. Hadlock FP1, Shah YP, Kanon DJ, Lindsey JV. Author information

Abstract Because of recent challenges in the literature regarding the validity of the older crown-rump length (CRL) data developed with conventional static-image ultrasound scanners, the authors evaluated the relationship between CRL and menstrual age of fetuses in a population of 416 patients with good menstrual dates. By using a variety of commercially available transabdominal and transvaginal real-time ultrasound probes, the authors demonstrated that measurements can be made successfully for CRLs varying in size from 2 mm to 12 cm. Regression analysis of the data resulted in development of a new table for predicting menstrual age of fetuses on the basis of CRL measurements obtained between 5 and 18 weeks gestation. Although the magnitude of the raw residuals increased over time, the variability in predicting menstrual age was demonstrated to be relatively constant at +/- 8% (2 standard deviations) when expressed as a percentage of the predicted value. The accuracy in predicting menstrual age from CRL after 14 weeks was equivalent to but not better than conventional measurements such as biparietal diameter and femur length. PMID 1732970

  1. Cussen L, Scurry J, Mitropoulos G, McTigue C & Gross J. (1990). Mean organ weights of an Australian population of fetuses and infants. J Paediatr Child Health , 26, 101-3. PMID: 2361065
  2. Hansen K, Sung CJ, Huang C, Pinar H, Singer DB & Oyer CE. (2003). Reference values for second trimester fetal and neonatal organ weights and measurements. Pediatr. Dev. Pathol. , 6, 160-7. PMID: 12548377 DOI.
  3. Archie JG, Collins JS & Lebel RR. (2006). Quantitative standards for fetal and neonatal autopsy. Am. J. Clin. Pathol. , 126, 256-65. PMID: 16891202 DOI.