File:Somatotopic Activation by corneal pain and eye blink.png
Somatotopic_Activation_by_corneal_pain_and_eye_blink.png (600 × 372 pixels, file size: 220 KB, MIME type: image/png)
Figure 1. Somatotopic activation triggered by combined corneal pain and eye blink.
The Pain+Blink condition activated contralateral S1 (Max zstat = 4.9 at 56, −14, 43) and bilateral M1 (Max zstat = 9.9 at 52, 2, 31) in regions corresponding to the eye in the Penfield sensory and motor homunculi [19] (p<0.0001, uncorrected for multiple comparisons). The No Pain+Blink condition activated bilateral M1 (Max zstat = 7.4 at 44, −4, 43), but not S1. Investigations were restricted to the non-shaded areas in the activation maps, which correspond to bilateral pre- (blue) and post-central gyri (red) as highlighted in the underlying brain slices and colored squares (dashed squares denote absent activation). Note that the boundaries of these probabilistic-defined areas overlap with other regions, such as supplementary motor area, middle frontal gyrus, and supramarginal gyrus. Of note, the supplementary motor area has previously been associated with voluntary blinking [13], and was active in both conditions along the midline of coronal slice y = −14 (only shown for Pain+Blink in figure). A = anterior; L = left; P = posterior; R = right.
Reference: E A Moulton, L Becerra An Approach to Localizing Corneal Pain Representation in Human Primary Somatosensory Cortex.PlosOne: 2012, Vol. 7, Issue 9, e44643, PMC3433421
Copyright: � 2012 Moulton et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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current | 17:28, 14 September 2012 | 600 × 372 (220 KB) | Z3332863 (talk | contribs) | Figure 1. Somatotopic activation triggered by combined corneal pain and eye blink. The Pain+Blink condition activated contralateral S1 (Max zstat = 4.9 at 56, −14, 43) and bilateral M1 (Max zstat = 9.9 at 52, 2, 31) in regions corresponding to the eye |
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