File:Hippocampal Formation.jpg

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Figure 1: Hippocampal formation.[1]

Images of the hippocampal formation at the level of the lateral geniculate body from (A) patient 1 and (C) patient 3 show abnormal expansion of CA1 by increased numbers of pyramidal neurons. These are compared with the more usual hippocampal microarchitecture that shows a thinner linear band of neurons in CA1, as seen in (B) a 62-year-old male control. Haematoxylin and eosin, original magnification ×10; scale bar = 1 mm. Arrow indicates bulge/expansion composed of increased numbers of pyramidal cells in (A) patient 1 and (C) patient 3.


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  1. C.M. Greco, C.S. Navarro, M.R. Hunsaker, I. Maezawa, J.F. Shuler, F. Tassone, M. Delany, J.W. Au, R.F Berman, L. Jin, C. Schumann, P.J. Hagerman and R.J. Hagerman Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Mol ecular Autism: 2011, 2(1):2.

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