Composite model for ethanol effects on fetal neural development

Ethanol causes assymetric neural stem cell (NSC) proliferation. This leads to premature depletion of NSCs in the ventricular zone (VZ) and the ultimately loss of reserve neuron generation capacity. The appearance of radial glial-like neuronal progenitors supports expansion, increases proliferation of neuronal progenitors in the sub-ventricular zone (SVZ) and increases migration of neuronal progenitor cells out of the VZ and SVZ, leading to the formation of heterotopias or displaced neuronal aggregates.

Reference

<pubmed>22623924</pubmed> Copyright: © 2012 Miranda. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.

Note - This image was originally uploaded as part of an undergraduate science student project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.