2012 Group Project 6

Hearing Development

Development

Inner Ear

The entire inner ear, as well as the neurons which innervate the sensory organ, are derived from the otic placode. The otic placode is a thickened portion of ectoderm located on the each side of the developing head of the embryo, next to the hindbrain. It is generally visible after gastrulation, once the first 5 to 10 pairs of somites have formed. Invagination occurs next, which creates the otocyst - a vesicle which will develop into the different components of the inner ear: the cochlea, the semicircular canals with cristae, the utricle, the saccule and the vestibulo-acoustic ganglion.

Induction of the otic placode

Experiments with molecular markers have revealed that several steps are needed for induction of the otic placode. We will consider the three major steps:

1 Pre-placodal domain

2 Pre-otic field

3 Otic placode/epidermis fate decision

External Links

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--Mark Hill 12:22, 15 August 2012 (EST) Please leave the content listed below the line at the bottom of your project page.

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2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing