2012 Group Project 5
Abnormal Vision
Introduction
Normal Eye Development
Retinal Development
Abnormal development
Genetic
Leber Congenital Amaurosis
Leber Congenital Amaurosis (LCA) is an inherited retinal degenerative disorder that causes blindness or loss of sight at birth.[1]
History
Research Timeline
From 1869-2009, the major contributers to LCA research: "Courtesy: National Eye Institute, National Institutes of Health (NEI/NIH)."
- 1869- Dr. Theodor Leber (1840-1917), German ophthalmologist, first describes what is now known as Leber congenital amaurosis, an inherited retinal disease that causes severe visual impairment early in childhood [2]
- 1932-34- George Wald, Ph.D. first identified vitamin A in the retina during a National Research Council fellowship in biology [3]
Epidemiology
LCA has a recessive pattern of inheritance where there is a 25% chance for a child to contract LCA.[4]
Aetiology
Pathology
Outcome and Treatment
New Research Development
Congenital Cataracts
Environmental
Glossary
References
- ↑ http://www.blindness.org/index.php?view=article&catid=38%3Aother-retinal-diseases&id=253%3Aleber-congenital-amaurosis&option=com_content&Itemid=88
- ↑ http://www.nei.nih.gov/lca/timeline.asp
- ↑ http://www.nei.nih.gov/lca/timeline.asp
- ↑ http://www.blindness.org/index.php?view=article&catid=38%3Aother-retinal-diseases&id=253%3Aleber-congenital-amaurosis&option=com_content&Itemid=88
External Links
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2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing