2011 Group Project 11
From Embryology
Note - This page is an undergraduate science embryology student group project 2011. |
Cleft Palate and Lip
Introduction
History
Development of Disease
Aetiology
Developmental Process
Developmental Staging
- Two main stages of palate development, primary and secondary
- Morphology of face established between weeks four and five
- 7th week – intermaxillary process formed, Intermaxillary process gives rise to primary palate
- End of 7th week – palantine shelves start to move into position and fuse together to form secondary palate
- Failure of these palantine shelves to fuse results in cleft palate
- Secondary palate fused during 10th week
- Cleft lip results in failure of the two maxillary processes to fuse with the descending part of the intermaxillary process
Abnormality Classification
- There has been a new proposed classification system
- Cleft palate and cleft lip have different embryological origins
- More than 300 syndromes involving facial clefting
- Can be unilateral or bilateral
- Cleft palate and cleft lip may be seen together or individually without the other one present
Pathophysiology
Genetic Configuration
Surgical Timeline
Current and Future Research
External Links
Glossary/Terms
Gallery
References
Textbooks
2011 Projects: Turner Syndrome | DiGeorge Syndrome | Klinefelter's Syndrome | Huntington's Disease | Fragile X Syndrome | Tetralogy of Fallot | Angelman Syndrome | Friedreich's Ataxia | Williams-Beuren Syndrome | Duchenne Muscular Dystrolphy | Cleft Palate and Lip