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The migration of neural crest cells into the mesenchymal tissues of the pharyngeal arches and subsequent differentiation into the bones of the craniofacial skeleton

The process of neural crest cell migration and differentiation leads to the development of specific craniofacial tissues.

Craniofacial clefts represent a deficiency, excess or absence of an embryonic developmental field, and subsequent impact on surrounding fields. The clinical significance of an understanding of the migration of neural crest cells is that it enables us to map out the anatomical site of origin for all zones of ectoderm and mesoderm supplied by a given zone of the nervous system which then allows for anatomical definition of congenital abnormalities such as cleft lip and or palate.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825068/

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current21:36, 9 October 2011Thumbnail for version as of 21:36, 9 October 2011771 × 333 (118 KB)Z3308968 (talk | contribs)The migration of neural crest cells into the mesenchymal tissues of the pharyngeal arches and subsequent differentiation into the bones of the craniofacial skeleton The process of neural crest cell migration and differentiation leads to the development o

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