File:Normal control muscle (a) vs. Duchennes muscular dystrophy muscle (b).jpg

Immunofluorescence with anti-AQP4 antibody of normal control muscle (a) and Duchenne muscular dystrophy muscle (DMD) (b), and that with anti-spectrin antibody of serial muscle section of DMD (c). Positive immunoreactivity with anti-AQP4 antibody is seen in apparently all myofibers of normal control muscles (a); while it is noted in mosaic pattern in DMD muscle (b). DMD muscle contains less numerous myofibers with positive immunoreactivity of anti-AQP4 antibody (b) than myofibers with that of anti-spectrin antibody (c). Scattered anti-AQP4 immunonegative fibers (asterisks in (b)) are noted in DMD muscle. Scale bar in (a)–(c) = 50μm.

Normal control muscle (a) vs. Duchennes muscular dystrophy muscle (b).jpg

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