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Lab 4 Online Assessment

The allantois, identified in the placental cord, is continuous with what anatomical structure?
Identify the 3 vascular shunts, and their location, in the embryonic circulation.
Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)

Lab 1 Assessment

1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique.

-The origin of IVF was in the UK in 1978 -The 2010 Nobel Prize winner was Robert G. Edwards for the development of this technique

2. Identify a recent paper on fertilisation and describe its key findings.

Recent Paper: "Trends in delivery and neonatal outcome after in vitro fertilization in Sweden: data for 25 years". B Klln, O Finnstrm, A Lindam, E Nilsson, K-G Nygren, P Otterblad Olausson. Hum. Reprod.: 2010, 25(4);1026-34 PMID:20139431

Key Findings: -The decrease in unwanted outcomes can be explained by a. the reduced rate of multiple births b. changes in the characteristics of patients undergoing IVF

3. Identify 2 congenital abnormalities.

-Trisomy 13 (Patau Syndrome) -Trisomy 21 (Down Syndrome)

Lab 2 Assessment

1. Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilisation.

ZP3 is a zona pellucida protein that spermatozoa binds to. Enzymes digest the zona pellucida after fertilisation which alters ZP3 so it will no longer bind sperm plasma membrane.

2. Identify a review and a research article related to your group topic. (Paste on both group discussion page with signature and on your own page)

Group topic: cystic fibrosis

Review article: H.A. Tiddens, Detecting early structural lung damage in cystic fibrosis, Pediatr Pulmonol 34 (3) (2002), pp. 228–231.

Research article: Wang SS, FitzSimmons SC, O'Leary LA, Rock MJ, Gwinn ML, Khoury MJ, Early diagnosis of cystic fibrosis in the newborn period and risk of Pseudomonas aeruginosa acquisition in the first 10 years of life: A registry-based longitudinal study, Pediatrics, 2001 Feb, 107(2):274-9.

--Fleur McGregor 12:51, 11 August 2011 (EST)