2009 Group Project 4

MOUSE

Timeline of Development

Staging

Theiler Stage (Scale in microns) Embryonic age in Days Post Coitum (dpc) Stage characteristic Cell characteristics Zona pellucida Location/ changes in site 1 0-0.9 (range 0-0.25) One-celled embryo (fertilized) One cell Present

2 1 (range 1-2.5) Dividing egg 2-4 cells - 1st cleavage after 24hrs Present

3 2 (range 1-3.5) Morula (early to fully compacted) 4-16 cells Present Oviduct. Usually near utero-tubal junction. 4 3 (range 2-4) Change from Morula to Blastocyst -Intra-cellular matrix -Blastocoelic cavity evident

16-40 compacted cells -Iinner cell mass -Outer layer of trophectoderm cells Present Uterine lumen 5 4 (range 3-5.5) Zona free Blastocyst

Absent Uterine lumen

History of Model Use

Genetics

Current Embryology Research

ANAT2341 group projects