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- 10:01, 14 August 2011 Z3290808 talk contribs uploaded File:FMR4 is silenced in fragile X syndrome.jpg (Pone.0001486.g003.jpg Figure 3 FMR4 is silenced in fragile X syndrome. (A) RNA from four normal, four premutation and four full mutation FXS patients isolated from untransformed leucocytes (kindly provided by Flora Tassone and Paul Hagerman, UC Davis) wa)