2014 Group Project 9
2014 Student Projects | ||||
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2014 Student Projects: Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8 | ||||
The Group assessment for 2014 will be an online project on Fetal Development of a specific System.
This page is an undergraduate science embryology student and may contain inaccuracies in either description or acknowledgements. |
Genital
Genital
System Development
(NB: having formatting issues trying to put the following information into a table, an attempt at the table is included below) Prior to discussing the fetal development of the genital system, it is important to briefly appreciate the embryonic development of the genital tracts. Up until the seventh week of development, male and female genital tracts are indifferent. The genital system begins from a thickening of the epithelium surrounding the mesonephros, which lies dorsally in the coelomic cavity. The proliferation of this coelomic epithelium leads to an outgrowth known as the genital ridge. The genital ridge continues in outgrowth due to the ingression of the polemic epithelium, proliferation and recruitment of adjacent mesonephric cells. This bipotential genital ridge is indifferent in XX and XY embryos, however due to chromosomal and genetic influences differentiate into the testis and ovary respectively. [1]
Fetal genital development occurs in three main stages 1. Differentiation of gonad into Ovary or Testis 2. Development of he internal genitalia 3. Development of the external genitalia
References [1] <pubmed>PMC3841730</pubmed> <pubmed>11315960</pubmed>
<pubmed>24240231</pubmed> <pubmed>24928207</pubmed> <pubmed>24741072</pubmed>
Related video
Current Research, Models and Findings
Current Research and Findings
Male
Extensive research into organogenesis of the external genitalia, mainly in males, is driven by the increasing incidence of hypospadias. Hypospadias are a result of the defect of fusion of the urethral folds of the lower part of the penis to fold and form the tubular penile urethra. The result of this in humans is the presence of an abnormal ventral urethral meatus, incomplete formation of the prepuce and an abnormal penile curvature.