File:Regulation of Nodal-Activin signalling during heart formation.png: Difference between revisions
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=Regulation of Nodal gradient and signalling activity= | ===Description=== | ||
''Figure 11'' | |||
====Regulation of Nodal gradient and signalling activity==== | |||
A model of signalling activity and gradients in mammals during the early stage of embryonic development provides clues for designing the initial stages of human pluripotent stem cells (hPSC) to cardiomyocyte differentiation. Nodal/Activin regulation is mediated by high Nodal production in epiblast cells, timed secretion of Nodal antagonists (cerberus and LEFTY1) by regions of the visceral endoderm, and autoregulatory feedback loops involving BMP4 and Wnt3 in proximal extraembryonic tissue. | A model of signalling activity and gradients in mammals during the early stage of embryonic development provides clues for designing the initial stages of human pluripotent stem cells (hPSC) to cardiomyocyte differentiation. Nodal/Activin regulation is mediated by high Nodal production in epiblast cells, timed secretion of Nodal antagonists (cerberus and LEFTY1) by regions of the visceral endoderm, and autoregulatory feedback loops involving BMP4 and Wnt3 in proximal extraembryonic tissue. | ||
Copyright | ===Reference=== | ||
<pubmed>25813860 </pubmed> | |||
===Copyright=== | |||
Articles published in these journals are in the public domain and may be used and reproduced without special permission. However, anyone using the material is requested to properly cite and acknowledge the source. | |||
{{Template:Student Image}} | {{Template:Student Image}} |
Revision as of 11:14, 13 October 2017
Description
Figure 11
Regulation of Nodal gradient and signalling activity
A model of signalling activity and gradients in mammals during the early stage of embryonic development provides clues for designing the initial stages of human pluripotent stem cells (hPSC) to cardiomyocyte differentiation. Nodal/Activin regulation is mediated by high Nodal production in epiblast cells, timed secretion of Nodal antagonists (cerberus and LEFTY1) by regions of the visceral endoderm, and autoregulatory feedback loops involving BMP4 and Wnt3 in proximal extraembryonic tissue.
Reference
<pubmed>25813860 </pubmed>
Copyright
Articles published in these journals are in the public domain and may be used and reproduced without special permission. However, anyone using the material is requested to properly cite and acknowledge the source.
- Note - This image was originally uploaded as part of an undergraduate science student project and may contain inaccuracies in either description or acknowledgements. Students have been advised in writing concerning the reuse of content and may accidentally have misunderstood the original terms of use. If image reuse on this non-commercial educational site infringes your existing copyright, please contact the site editor for immediate removal.
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