Template talk:Liver Vignette
In 1666 two years later they were again described by Malpighi who gave them their name. Malpighi states that the livers of all vertebrates are conglomerate glands, being composed of lobules which in turn contain acini. For a long time after this the capital problem in the anatomy of the liver was the study of the structure of the lobules and their relation to one another.
Wepfer 1664 described lobules in the liver of the pig.