File:Somatotopic Activation by corneal pain and eye blink.png

Somatotopic activation triggered by combined corneal pain and eye blink

The Pain+Blink condition activated contralateral S1 (Max zstat = 4.9 at 56, −14, 43) and bilateral M1 (Max zstat = 9.9 at 52, 2, 31) in regions corresponding to the eye in the Penfield sensory and motor homunculi [19] (p<0.0001, uncorrected for multiple comparisons). The No Pain+Blink condition activated bilateral M1 (Max zstat = 7.4 at 44, −4, 43), but not S1.

Investigations were restricted to the non-shaded areas in the activation maps, which correspond to bilateral pre- (blue) and post-central gyri (red) as highlighted in the underlying brain slices and colored squares (dashed squares denote absent activation).

Note that the boundaries of these probabilistic-defined areas overlap with other regions, such as supplementary motor area, middle frontal gyrus, and supramarginal gyrus. Of note, the supplementary motor area has previously been associated with voluntary blinking [13], and was active in both conditions along the midline of coronal slice y = −14 (only shown for Pain+Blink in figure).

A = anterior; L = left; P = posterior; R = right.

Reference

<pubmed>22973463</pubmed>| PlosOne

Copyright: 2012 Moulton et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1.

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--Mark Hill 12:06, 15 September 2012 (EST) I have fixed this referencing section, which is normally done by the student, please add new images with similar information.