ANAT2341 Lab 3

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1. QUIZ

2. Mark Hill (UNSW) – Group Projects

Today you will be sitting with your fellow group members during the lab class, look for your group number on the benches.

  1. Select group topic and access project discussion page. (Add your signature to the discussion page)
  2. Allocate initial research areas. (these may change over time)
  3. Commence online topic research. (Journal Searches)


Projects 2018: 1 Adrenal Medulla | 3 Melanocytes | 4 Cardiac | 5 Dorsal Root Ganglion



2018 Test Student

Main Topic

Human embryo week 4 neural crest cells
Human embryo neural crest cells (Week 4, Carnegie stage 11)

The term "neural crest was first used in Marshall A. The morphology of the vertebrate olfactory organ. (1879) Quarterly Journal of Microscopic Science. 19: 300–340..


From the main topic, each group will select their own sub-topic. Below are the existing online information pages.


Neural Crest

Neural Crest Links: neural crest | Lecture - Early Neural | Lecture - Neural Crest Development | Lecture Movie | Schwann cell | adrenal | melanocyte | peripheral nervous system | enteric nervous system | cornea | cranial nerve neural crest | head | skull | cardiac neural crest | Nicole Le Douarin | Neural Crest Movies | neural crest abnormalities | Category:Neural Crest
Historic Embryology - Neural Crest  
1879 Olfactory Organ | 1905 Cranial and Spinal Nerves | 1908 10 mm Peripheral | 1910 Mammal Sympathetic | 1920 Human Sympathetic | 1939 10 Somite Embryo | 1942 Origin | 1957 Adrenal
Neural Crest Origin
System Cell Type
Peripheral Nervous System
(PNS)
Neurons - sensory ganglia, sympathetic and parasympathetic ganglia, enteric nervous system, and plexuses

Neuroglial cells, olfactory ensheathing cells[1]

Schwann cells[2]

Endocrine Adrenal medulla
Calcitonin-secreting cells
Carotid body type I cells
Integumentary Epidermal pigment cells melanocyte
Facial cartilage and bone Facial and anterior ventral skull cartilage and bones
Sensory inner ear, cornea endothelium and stroma
Connective tissue Tooth odontoblast

smooth muscle, and adipose tissue of skin of head and neck

Connective tissue of meninges, salivary, lachrymal, thymus, thyroid, and pituitary glands

Connective tissue and smooth muscle in arteries of aortic arch origin

Links: Neural Crest Development | Category:Neural Crest | Neural Crest collapsible table



  1. Barraud P, Seferiadis AA, Tyson LD, Zwart MF, Szabo-Rogers HL, Ruhrberg C, Liu KJ & Baker CV. (2010). Neural crest origin of olfactory ensheathing glia. Proc. Natl. Acad. Sci. U.S.A. , 107, 21040-5. PMID: 21078992 DOI.
  2. Woodhoo A & Sommer L. (2008). Development of the Schwann cell lineage: from the neural crest to the myelinated nerve. Glia , 56, 1481-90. PMID: 18803317 DOI.

Online Research Database

PubMed logo.gif
  • The online projects generally as a main source the PubMed database.



About Journal Searches  
The following general information is about the above online databases and journals.

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.

  • PubMed - comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
    • PubMed Central (PMC) - is a free full-text archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health's National Library of Medicine (NIH/NLM).
  • Public Library of Science (PLOS) - is a nonprofit publisher and advocacy organization founded to accelerate progress in science and medicine by leading a transformation in research communication.
  • BioMed Central (BMC) - is an STM (Science, Technology and Medicine) publisher of 291 peer-reviewed open access journals.
    • BMC Developmental Biology - is an open access, peer-reviewed journal that considers articles on the development, growth, differentiation and regeneration of multicellular organisms, including molecular, cellular, tissue, organ and whole organism research.
    • Reproductive Health - is an open access, peer-reviewed online journal focusing on all aspects of human reproduction.
    • Reproductive Biology and Endocrinology (RB&E) - aims to act as a forum for the dissemination of results from excellent research in the reproductive sciences. RB&E represents a global platform for reproductive and developmental biologists, reproductive endocrinologists, immunologists, theriogenologists, infertility specialists, obstetricians, gynecologists, andrologists, urogynecologists, specialists in menopause, reproductive tract oncologists, and reproductive epidemiologists.
  • Biology Open (BiO) - is an online-only Open Access journal that publishes peer-reviewed original research across all aspects of the biological sciences, including cell science, developmental biology and experimental biology.

Searching

PubMed Reference Search - neural crest
Code:

PubMed Reference Search - [https://www.ncbi.nlm.nih.gov/search/?term=neural+crest neural crest]


PMC Image Search - neural crest
Code:

PMC Image Search - [http://www.ncbi.nlm.nih.gov/pmc/?term=neural+crest&report=imagesdocsum neural crest]


Nadege Bondurand, Sylvie Dufour, Veronique Pingault News from the Endothelin-3/EDNRB signaling pathway: role during enteric nervous system development and involvement in neural crest-associated disorders. Dev. Biol.: 2018; PubMed 30171849

Warren J Scherer Corneal endothelial cell density and cardiovascular mortality: A Global Survey and Correlative Meta-Analysis. Clin Anat: 2018; PubMed 30168608

Daniel Terheyden-Keighley, Xiaoqing Zhang, Beate Brand-Saberi, Carsten Theiss ##Title## Biol Open: 2018; PubMed 30135081

Hatem A Tawfik, Jonathan J Dutton Embryologic and Fetal Development of the Human Orbit. Ophthalmic Plast Reconstr Surg: 2018; PubMed 30134385

Jean-Claude Dupont Historical perspective on neuroembryology: Wilhelm His and his contemporaries. Genesis: 2018, 56(6-7);e23218 PubMed 30134065



Code:

<pubmed limit=5>Neural Crest Embryology</pubmed>

Citing Published Papers

You must clearly separate these 2 types of papers when citing on the project page. Hint - PubMed indicates when the paper is a review.

  1. Research paper is based on original research.
  2. Review paper is based on other published articles. It does not report original research and generally summarize the existing literature on a topic in an attempt to explain the current state of understanding on the topic.


Any stated finding on your project page, must cite a research paper(s).

Any paper that usefully summarises a research topic (a review), must indicate in the text that the citation is a review.

For example: "see review", "as reviewed by", "best summarised by the review"......


Alternatively, consider a subheading that lists just the reviews in some sequence/topic.

Here is an example of a recent neural crest review article.[1]



  1. Bronner ME & Simões-Costa M. (2016). The Neural Crest Migrating into the Twenty-First Century. Curr. Top. Dev. Biol. , 116, 115-34. PMID: 26970616 DOI.

Project Structure

  1. Begin by looking at previous project pages and see which structure/organisation appears best to you.
  2. Add suggested sub-headings to the project page and see if the organisation makes sense.
  3. Remember that sub-heading structure can be changed at any time or "undo" to an earlier structure (note if you "undo" all later version changes will be lost).



Here are some useful concepts to consider including (listed in no specific order):

  • introduction
  • history
  • embryonic origins
  • developmental time course
  • developmental/adult function
  • tissue/organ structure
  • molecular mechanisms/factors/genes
  • abnormalities/abnormal development
  • animal models
  • current research (labs)
  • glossary
  • reference list






Editing Links: Editing Basics | Images | Tables | Referencing | Journal Searches | Copyright | Font Colours | Virtual Slide Permalink | My Preferences | One Page Wiki Card | Printing | Movies | Language Translation | Student Movies | Using OpenOffice | Internet Browsers | Moodle | Navigation/Contribution | Term Link | Short URLs | 2018 Test Student
 2018 ANAT2341 - Timetable | Course Outline | Moodle | Tutorial 1 | Tutorial 2 | Tutorial 3

Labs: 1 Preimplantation and Implantation | 2 Reproductive Technology Revolution | 3 Group Projects | 4 GM manipulation mouse embryos | 5 Early chicken eggs | 6 Female reproductive tract | 7 Skin regeneration | 8 Vertebral development | 9 Organogenesis Lab | 10 Cardiac development | 11 Group projects | 12 Stem Cell Journal Club

Lectures: 1 Introduction | 2 Fertilization | 3 Week 1/2 | 4 Week 3 | 5 Ectoderm | 6 Placenta | 7 Mesoderm | 8 Endoderm | 9 Research Technology | 10 Cardiovascular | 11 Respiratory | 12 Neural crest | 13 Head | 14 Musculoskeletal | 15 Limb | 16 Renal | 17 Genital | 18 Endocrine | 19 Sensory | 20 Fetal | 21 Integumentary | 22 Birth | 23 Stem cells | 24 Revision

 Student Projects: Group Projects Information Project 1 | Project 2 | Project 3 | Project 4 | Project 5 | 2018 Test Student | Copyright