Musculoskeletal System - Muscle Development

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Introduction

There are 3 different types of muscle: skeletal, cardiac and smooth. This page describes skeletal muscle development, descriptions of cardiac muscle and smooth muscle development can be found in other notes. (More? Cardiac or GIT Development)

Skeletal muscle forms by fusion of mononucleated myoblasts to form mutinucleated myotubes.

Differentiation/determination of mesoderm into muscle cells is thought to involve a family of basic Helix-Loop-Helix transcription factors, the first of which discovered was MyoD1. (see OMIM entry). It needs to form a dimer to be active and is maintained in an inactive state by binding of Id (see OMIM entry).

Musculoskeletal Links: Introduction | mesoderm | somitogenesis | limb | cartilage | bone | bone timeline | bone marrow | shoulder | pelvis | axial skeleton | skull | joint | skeletal muscle | muscle timeline | tendon | diaphragm | Lecture - Musculoskeletal | Lecture Movie | musculoskeletal abnormalities | limb abnormalities | developmental hip dysplasia | cartilage histology | bone histology | Skeletal Muscle Histology | Category:Musculoskeletal
Historic Embryology - Musculoskeletal  
1853 Bone | 1885 Sphenoid | 1902 - Pubo-femoral Region | Spinal Column and Back | Body Segmentation | Cranium | Body Wall, Ribs, and Sternum | Limbs | 1901 - Limbs | 1902 - Arm Development | 1906 Human Embryo Ossification | 1906 Lower limb Nerves and Muscle | 1907 - Muscular System | Skeleton and Limbs | 1908 Vertebra | 1908 Cervical Vertebra | 1909 Mandible | 1910 - Skeleton and Connective Tissues | Muscular System | Coelom and Diaphragm | 1913 Clavicle | 1920 Clavicle | 1921 - External body form | Connective tissues and skeletal | Muscular | Diaphragm | 1929 Rat Somite | 1932 Pelvis | 1940 Synovial Joints | 1943 Human Embryonic, Fetal and Circumnatal Skeleton | 1947 Joints | 1949 Cartilage and Bone | 1957 Chondrification Hands and Feet | 1968 Knee
System Links: Introduction | Cardiovascular | Coelomic Cavity | Endocrine | Gastrointestinal Tract | Genital | Head | Immune | Integumentary | Musculoskeletal | Neural | Neural Crest | Placenta | Renal | Respiratory | Sensory | Birth


--Mark Hill 09:25, 14 April 2010 (EST) Page Template only - content from original UNSW Embryology site currently being edited and updated.


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Cite this page: Hill, M.A. (2024, May 19) Embryology Musculoskeletal System - Muscle Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Musculoskeletal_System_-_Muscle_Development

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G