Gastrointestinal Tract - Gall Bladder Histology: Difference between revisions
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#REDIRECT [[Gastrointestinal Tract - Gallbladder Histology]] | |||
==Introduction== | ==Introduction== | ||
[[File:Gray1096.jpg|thumb|300px|Gall bladder transverse section historic drawing.]] | [[File:Gray1096.jpg|thumb|300px|Gall bladder transverse section historic drawing.]] | ||
This section of notes gives an overview mainly of adult gall bladder histology, see also [[Gastrointestinal Tract - Gall_Bladder_Development|Gall Bladder Development]] notes. | This section of notes gives an overview mainly of adult gall bladder histology, see also [[Gastrointestinal Tract - Gall_Bladder_Development|Gall Bladder Development]] notes. | ||
[[File:HMsmall.jpg|left]] Page also provides further background information for Medicine phase 1 Health Maintenance B Hepatobiliary System 2 Practical [http://vslides.unsw.edu.au/VirtualSlideV2.nsf/id/9F207C Virtual Slides]. | [[File:HMsmall.jpg|left]] Page also provides further background information for Medicine phase 1 Health Maintenance B Hepatobiliary System 2 Practical [http://vslides.unsw.edu.au/VirtualSlideV2.nsf/id/9F207C Virtual Slides]. '''This page content is not part of the HMB practical class.''' | ||
::[[Gastrointestinal_Tract_-_Liver_Histology|Liver Histology]] | [[Gastrointestinal_Tract_-_Gall_Bladder_Histology|Gall Bladder Histology]] | [[Renal System Histology]] | |||
::'''HMB:''' [[Gastrointestinal Tract - Pancreas Histology|Pancreas Histology]] | [[Gastrointestinal_Tract_-_Liver_Histology|Liver Histology]] | [[Gastrointestinal_Tract_-_Gall_Bladder_Histology|Gall Bladder Histology]] | [[Renal System Histology]] | |||
{{Template:Gastrointestinal Tract Links}} | {{Template:Gastrointestinal Tract Links}} | ||
===Lab Audio=== | |||
[[File:Podcast_icon.jpg]] Wednesday 24 August 2011 3-3:30 pm G2G4. | |||
{{AudioHMBGallBladder2011}} | |||
==Gall Bladder Structure== | ==Gall Bladder Structure== | ||
===Anatomy=== | |||
* Pear-shaped | |||
* distensible sac (about 50ml volume) | |||
* Attached to posterioinferior surface of liver | |||
* Embryonic - foregut, forms from primitive bile duct | |||
* leads to cystic duct | |||
** Liver -> hepatic duct | |||
** Gall bladder -> cystic duct | |||
** Common Bile duct | |||
Macroscopic Mucosal features: | |||
* Mucosa (epithelium + lamina propria) | |||
** Mucosal folds | |||
** Rokitansky-Aschoff sinuses | |||
* Serosa/Adventitia (dense CT + visceral mesothelium) | |||
===Epithelium=== | |||
* Columnar epithelium with microvilli (absorptive epithelium) | |||
** Epithelium lining the biliary system does not contain mucus-producing cells (few located in neck of gall bladder) | |||
* Basement membrane (not basal lamina which forms part of basement membrane and only visible by EM) | |||
===Lamina Propria=== | |||
* connective tissue | |||
* collagen fibers and fibroblasts | |||
* fenestrated capillaries and venules | |||
* lymphocytes and plasma cells | |||
===Smooth Muscle Layer=== | |||
* random orientation of smooth muscle cells (fibers) | |||
* '''muscularis propria''' (or fibromuscular coat)<ref><pubmed>21074688</pubmed></ref> | |||
** not like the rest of GIT smooth muscle organisation, which is divided into muscularis mucosa (inside submucosa), muscularis externa (circular and longitudinal) | |||
** various terminology used for this layer in different sources | |||
===Serosa/Adventitia=== | |||
* Dense connective tissue layer covered with visceral mesothelium epithelial layer | |||
** Adventitia - where it is attached to the liver | |||
** Serosa - where it is free in the peritoneum | |||
* Large blood vessels (arteries, veins) | |||
* Obvious lymphatic vessels | |||
* Autonomic nerve bundles | |||
* Adipose tissue | |||
==Gall Bladder Function== | |||
* bile storage | |||
* bile concentration | |||
* bile release | |||
==Histology Images== | ==Histology Images== | ||
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[[File:Gall_bladder_histology_003.jpg|400px]] [[File:Gall_bladder_histology_004.jpg|400px]] | [[File:Gall_bladder_histology_003.jpg|400px]] [[File:Gall_bladder_histology_004.jpg|400px]] | ||
See also [[:File:Gall bladder histology 005.gif|Animated labeled image]] | |||
==References== | |||
<references/> | |||
==Historic== | |||
[[Embryology Historic Terminology]] | |||
* '''Luschka ducts''' (duct of Luschka) is historic term referring to an accessory bile duct. | |||
* '''folds of Heister''' (spiral valves of Heister) are undulating folds containing muscle fibers in the proximal mucosa of the cystic duct. First described by Heister in 1732. [https://www.ncbi.nlm.nih.gov/pubmed/15696536 PMID: 15696536] | |||
==External Links== | ==External Links== | ||
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{{ | {{Glossary}} | ||
{{ | {{Footer}} | ||
Latest revision as of 13:42, 23 January 2019
Redirect to:
Introduction
This section of notes gives an overview mainly of adult gall bladder histology, see also Gall Bladder Development notes.
Page also provides further background information for Medicine phase 1 Health Maintenance B Hepatobiliary System 2 Practical Virtual Slides. This page content is not part of the HMB practical class.
Lab Audio
Wednesday 24 August 2011 3-3:30 pm G2G4.
- Links: listen 1 | download 1 | listen 2 | download 2 | listen 3 | download 3 | listen 4 | download 4 | Gall Bladder Histology Background
Gall Bladder Structure
Anatomy
- Pear-shaped
- distensible sac (about 50ml volume)
- Attached to posterioinferior surface of liver
- Embryonic - foregut, forms from primitive bile duct
- leads to cystic duct
- Liver -> hepatic duct
- Gall bladder -> cystic duct
- Common Bile duct
Macroscopic Mucosal features:
- Mucosa (epithelium + lamina propria)
- Mucosal folds
- Rokitansky-Aschoff sinuses
- Serosa/Adventitia (dense CT + visceral mesothelium)
Epithelium
- Columnar epithelium with microvilli (absorptive epithelium)
- Epithelium lining the biliary system does not contain mucus-producing cells (few located in neck of gall bladder)
- Basement membrane (not basal lamina which forms part of basement membrane and only visible by EM)
Lamina Propria
- connective tissue
- collagen fibers and fibroblasts
- fenestrated capillaries and venules
- lymphocytes and plasma cells
Smooth Muscle Layer
- random orientation of smooth muscle cells (fibers)
- muscularis propria (or fibromuscular coat)[1]
- not like the rest of GIT smooth muscle organisation, which is divided into muscularis mucosa (inside submucosa), muscularis externa (circular and longitudinal)
- various terminology used for this layer in different sources
Serosa/Adventitia
- Dense connective tissue layer covered with visceral mesothelium epithelial layer
- Adventitia - where it is attached to the liver
- Serosa - where it is free in the peritoneum
- Large blood vessels (arteries, veins)
- Obvious lymphatic vessels
- Autonomic nerve bundles
- Adipose tissue
Gall Bladder Function
- bile storage
- bile concentration
- bile release
Histology Images
Development Histology
Adult Histology
See also Animated labeled image
References
- ↑ <pubmed>21074688</pubmed>
Historic
Embryology Historic Terminology
- Luschka ducts (duct of Luschka) is historic term referring to an accessory bile duct.
- folds of Heister (spiral valves of Heister) are undulating folds containing muscle fibers in the proximal mucosa of the cystic duct. First described by Heister in 1732. PMID: 15696536
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- Blue Histology Gall Bladder
- UNSW Virtual Slides Medicine phase 1 Health Maintenance B Hepatobiliary System 2 Practical (requires login for access).
- UIOWA Virtual Slidebox of Histology Liver and biliary system
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, May 19) Embryology Gastrointestinal Tract - Gall Bladder Histology. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Gastrointestinal_Tract_-_Gall_Bladder_Histology
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G