Talk:Abnormal Development - Lymphocytic Choriomeningitis Virus
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Cite this page: Hill, M.A. (2024, May 28) Embryology Abnormal Development - Lymphocytic Choriomeningitis Virus. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Abnormal_Development_-_Lymphocytic_Choriomeningitis_Virus |
2006
Lymphocytic choriomeningitis virus: an emerging obstetric pathogen?
Am J Obstet Gynecol. 2006 Jun;194(6):1532-6. Epub 2006 Apr 21.
Jamieson DJ, Kourtis AP, Bell M, Rasmussen SA. Source Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Abstract
A report in May 2005 from the Centers for Disease Control and Prevention describing a cluster of lymphocytic choriomeningitis virus (LCMV) infections among 4 solid organ recipients has increased awareness of and clinical interest in this pathogen. Human infection with LCMV results from direct or indirect contact with rodents. LCMV has particular relevance to obstetrics, as it is likely an under-recognized abortifacient and fetal teratogen. There have been 54 cases of congenital LCMV reported since 1955, with 34 of the cases diagnosed since 1993. Chorioretinitis and hydrocephalus are the predominant characteristics among children diagnosed with congenital LCMV infection. Obstetricians should educate their pregnant patients about the risks of exposure to laboratory, pet, and wild rodents.
PMID 16731068
2002
Lymphocytic choriomeningitis virus: emerging fetal teratogen
Am J Obstet Gynecol. 2002 Dec;187(6):1715-6.
Barton LL, Mets MB, Beauchamp CL. Source Department of Pediatrics and Steele Memorial Children's Research Center, University of Arizona, Tucson 85724, USA. llb@peds.arizona.edu Abstract Lymphocytic choriomeningitis virus (LCMV), a rodent-borne arenavirus, is an often undiagnosed human fetal teratogen. We describe a neonate born with hydrocephalus and chorioretinitis after maternal second-trimester symptomatic LCMV infection. Previously reported affected infants are reviewed. We strongly suggest that obstetricians counsel their pregnant patients regarding the potential hazard that contact with infected pet, laboratory, and household mice and hamsters poses to pregnant women and their unborn children.
PMID 12501090