File:Adrenal histology 002.jpg
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Adrenal Cortex
Adrenal gland, monkey - (Stain - Haematoxylin Eosin) Adrenal Development
Divided into three zones (Adrenocorticotropic hormone (ACTH) required for zones 2 and 3)
- zona glomerulosa (about 15%)
- zona fasciculata (about 75%)
- zone reticularis is (about 10%)
Note the adrenal zona reticularis is a layer that forms postnatally in the cortex.
Zona Glomerulosa
- secretes mineralocorticoids.
- Small cells arranged into small rounded groups or curved columns.
- not influenced by ACTH.
Zona Fasciculata
- secretes glucocorticoids.
- cell cords arranged radially arranged cell cords separated by fenestrated sinusoid capillaries.
- cell nucleus is light and centrally located.
- cell cytoplasm is also light and often "foamy" or "spongy" appearance (due to lipid droplets)
Zona Reticularis
- secretes adrenal androgens.
- cell chords separated by sinusoid spaces.
- small cells with large nucleus, and eosinophilic cytoplasm and less spongy. (lipofucsin accumulates with age, orange colour in H&E).
- Adrenal Histology: Cortex and Medulla | Unlabelled Overview | Cortical Zones | Zona Glomerulosa and Fasciculata | Zona Glomerulosa | Zona Fasciculata | Zona Reticularis and Medulla | Zona Reticularis | Medulla | Fetal Cortex | Developing Adult Cortex | BGD - Endocrine Histology | Histology Stains | Adrenal Development
Links: Histology | Histology Stains | Blue Histology images copyright Lutz Slomianka 1998-2009. The literary and artistic works on the original Blue Histology website may be reproduced, adapted, published and distributed for non-commercial purposes. See also the page Histology Stains.
Cite this page: Hill, M.A. (2024, June 3) Embryology Adrenal histology 002.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Adrenal_histology_002.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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