Integumentary System - Nail Development
From Embryology
Notice - Mark Hill
Currently this page is only a template and is being updated (this notice removed when completed).Introduction
Some Recent Findings
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Textbooks
- Human Embryology (2nd ed.) Larson Chapter 14 p443-455
- The Developing Human: Clinically Oriented Embryology (6th ed.) Moore and Persaud Chapter 20: P513-529
- Before We Are Born (5th ed.) Moore and Persaud Chapter 21: P481-496
- Essentials of Human Embryology Larson Chapter 14: P303-315
- Human Embryology, Fitzgerald and Fitzgerald
- Color Atlas of Clinical Embryology Moore Persaud and Shiota Chapter 15: p231-236
Development Overview
- Forelimb before hindlimb - week 10 fingernails, week 14 toe nails
- nail field - appears at tip and migrates to dorsal surface
- thickened epidermis - surrounding cells form nail fold
- keratinization of proximal nail fold forms nail plate
Nails reach Digit Tip
- week 32 fingernails
- week 36 toenails
- nail growth indicator of prematurity
Abnormalities
Anonychia
A very rare abnormality resulting in an absence of nails. Can result from both genetic and environmental defects and be associated with a range of other abnormalities. Simple anonychia is the congenital absence of the nails without any other coexisting major congenital anomaly.
Nail-patella syndrome
Witkop syndrome
An autosomal dominant genetic disorder characterized by the absence of several teeth and abnormalities of the nails.
References
Journals
Reviews
Articles
Search PubMed
Search Pubmed: Nail Development
Additional Images
Terms
- nail plate - visible part of the nail
- nail bed - skin beneath the nail plate
- cuticle - tissue that overlaps the plate and rims the base of the nail
- nail folds - skin folds that frame and support the nail on three sides
- lunula - half-moon at the base of the nail
- matrix - hidden part of the nail unit under the cuticle
External Links
Embryo Images - Human (day 64) primary nail fields
Glossary Links
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Cite this page: Hill, M.A. (2024, June 14) Embryology Integumentary System - Nail Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Integumentary_System_-_Nail_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G