Endocrine - Thyroid Development: Difference between revisions

Revision as of 14:07, 25 April 2010

Historic Embryology - Endocrine
1903 Islets of Langerhans \| 1903 Pig Adrenal \| 1904 interstitial Cells \| 1908 Pancreas Different Species \| 1908 Pituitary \| 1908 Pituitary histology \| 1911 Rathke's pouch \| 1912 Suprarenal Bodies \| 1914 Suprarenal Organs \| 1915 Pharynx \| 1916 Thyroid \| 1918 Rabbit Hypophysis \| 1920 Adrenal \| 1935 Mammalian Hypophysis \| 1926 Human Hypophysis \| 1927 Adrenal \| 1927 Hypophyseal fossa \| 1930 Adrenal \| 1932 Pineal Gland and Cysts \| 1935 Hypophysis \| 1935 Pineal \| 1937 Pineal \| 1935 Parathyroid \| 1940 Adrenal \| 1941 Thyroid \| 1950 Thyroid Parathyroid Thymus \| 1957 Adrenal

Functions from wk10, required for neural development, stimulates metabolism (protein, carbohydrate, lipid), reduced/absence = cretinism (see abnormalities)

Hormones - (amino acid derivatives) Thyroxine (T4), Triiodothyronine (T3)

Stage 13 and Stage 22 thyroid development

foramen caecum

thyroid median endodermal thickening in the floor of pharynx, outpouch – thyroid diverticulum
tongue grows, cells descend in neck
thyroglossal duct - proximal end at the foramen cecum of tongue thyroglossal duct
thyroid diverticulum - hollow then solid, right and left lobes, central isthmus

24 days - thyroid median endodermal thickening in the floor of pharynx, outpouch – thyroid diverticulum
Week 11 - colloid appearance in thyroid follicles, iodine and thyroid hormone (TH) synthesis

growth factors (insulin-like, epidermal) stimulates follicular growth

Initial secreted biologically inactivated by modification, late fetal secretion develops brown fat
Iodine deficiency- during this period, leads to neurological defects (cretinism)
Birth - TSH levels increase, thyroxine (T3) and T4 levels increase to 24 h, then 5-7 days postnatal decline to normal levels

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Cite this page: Hill, M.A. (2024, June 3) Embryology Endocrine - Thyroid Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Endocrine_-_Thyroid_Development

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 ===Adult Histology===
 <gallery>
-File:Pineal_histology_001.jpg|Pineal (high power)
+File:Thyroid_histology_001.jpg|Thyroid (low power)
+File:Thyroid_histology_002.jpg|Thyroid (high power)
 </gallery>