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* '''Maternal effects and cancer risk in the progeny of mice exposed to X-rays before conception'''<ref>15945274</ref> "To investigate in an animal model whether preconceptual X-ray exposure leads to an altered tumor rate and spectrum in the offspring, a transgeneration carcinogenesis study was carried out. Female mice received X-ray irradiation (2 x 2 Gray) 2 weeks prior to mating with untreated males. ... Fertility and the lifetime of the maternal mice were reduced by the X-ray irradiation, and their incidence of lung and liver tumors was increased as compared to non-irradiated mice. The descendants of all groups revealed comparable body weights and mortality rates. The incidence of hematopoietic/lymphoreticular tissue tumors increased in the female hybrids by 6 months of CsA-treatment. A higher incidence of lung and liver tumors in the sham-treated male progeny of irradiated mothers was detected, pointing to a possible germ cell-transmitted alteration initiated by the preconceptual maternal X-ray exposure." | * '''Maternal effects and cancer risk in the progeny of mice exposed to X-rays before conception'''<ref><pubmed>15945274</pubmed></ref> "To investigate in an animal model whether preconceptual X-ray exposure leads to an altered tumor rate and spectrum in the offspring, a transgeneration carcinogenesis study was carried out. Female mice received X-ray irradiation (2 x 2 Gray) 2 weeks prior to mating with untreated males. ... Fertility and the lifetime of the maternal mice were reduced by the X-ray irradiation, and their incidence of lung and liver tumors was increased as compared to non-irradiated mice. The descendants of all groups revealed comparable body weights and mortality rates. The incidence of hematopoietic/lymphoreticular tissue tumors increased in the female hybrids by 6 months of CsA-treatment. A higher incidence of lung and liver tumors in the sham-treated male progeny of irradiated mothers was detected, pointing to a possible germ cell-transmitted alteration initiated by the preconceptual maternal X-ray exposure." | ||
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==Musculoskeletal Abnormalities== | ==Musculoskeletal Abnormalities== |
Revision as of 10:35, 15 September 2011
Educational Use Only - Embryology is an educational resource for learning concepts in embryological development, no clinical information is provided and content should not be used for any other purpose. |
Introduction
There are a number of different neonatal screening (newborn screening) programs in different countries testing for various "common" abnormalities and infections. These include physical tests for hip displasia.
Diagnosis Categories
- Prenatal diagnosis - number of different techniques (non-invasive, invasive) for determining normal development
- Neonatal diagnosis (APGAR test, Guthrie test, Hearing test)
- Maternal diagnosis - often pregnancy will expose maternal health problems
Some Recent Findings
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Musculoskeletal Abnormalities
Congenital Hip Dislocation
(>>) right hip dysplasia is shown. |
Arthrogryposis
Renal Abnormalities
Renal Agenesis
Ureteral Duplication
Gastrointestinal Tract Abnormalities
Duodenal atresia
Gene Tests
A new site developed by NIH "GeneTests" provides medical genetics information resources available at no cost to all interested persons. It contains educational information, a directory of genetic testing laboratories and links to other databases such as OMIM.
Links: Gene Tests
References
- ↑ <pubmed>15945274</pubmed>
Reviews
Articles
Search PubMed
Search PubMed: x-ray neonatal diagnosis | x-ray neonatal screening | maternal x-ray risk
Additional Images
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- NIH PubMed Health Newborn Screening
- Nemours Foundation Newborn Screening Tests
- The Children's Hospital at Westmead NSW Newborn Screening
- Secondary School Resource biotechnology online
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 18) Embryology X-ray. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/X-ray
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G