Difference between revisions of "Vision - Retina Development"
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Vertebrates have ten identifiable layers formed from neurons, their processes (nerve fibers), membranes, photoreceptors and pigmented cells. Light must pass through nearly all these layers to the photoreceptors.
- Inner limiting membrane - Müller cell footplates.
- Nerve fiber layer - retinal ganglion axons eventually the optic nerve.
- Ganglion cell layer - neuronal cell bodies of retinal ganglion cells, their axons form the nerve fiber layer and eventually the optic nerve.
- Inner plexiform layer - another layer of neuronal processes.
- Inner nuclear layer - neuronal cell bodies
- Outer plexiform layer - another layer of neuronal processes.
- Outer nuclear layer - neuronal cell bodies
- External limiting membrane - layer separating inner segment portions of photoreceptors from their cell nuclei.
- Photoreceptor layer - rods and cones that convert light into signals.
- Retinal pigment epithelium.
Retinal Pigment Epithelium
Retinal pigment epithelium (RPE) cells are generated directly from the optic neuroepithelium. The choroidal melanocytes, the other pigmented cells, are derived from neural crest cells that have migrated towards the eye.
Retinal pigment epithelium cells:
- cuboidal cells
- apical side form multiple villi
- these villi are in direct contact with the outer segments of the photoreceptor cells
- lateral sides are joined together by tight, adherens and gap junctions
- basal side contacts the underlying basal membrane (Bruch’s membrane)
- <pubmed>12186651</pubmed>| Genome Biol.
- The International Journal of Developmental Biology (2004) Eye Development
<pubmed>19750521</pubmed> <pubmed>19427305</pubmed> <pubmed>18374618</pubmed> <pubmed>17914430</pubmed> <pubmed>17692298</pubmed> <pubmed>16920202</pubmed>
Bookshelf retina development
<pubmed>20532172</pubmed> <pubmed>20503381</pubmed> <pubmed>20237275</pubmed> <pubmed>20206598</pubmed> <pubmed>20152110</pubmed> <pubmed>20150723</pubmed> <pubmed>20130177</pubmed> <pubmed>20014102</pubmed> <pubmed>19933188</pubmed>
Search Pubmed: retina embryology
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Cite this page: Hill, M.A. (2021, April 17) Embryology Vision - Retina Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Vision_-_Retina_Development
- © Dr Mark Hill 2021, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G