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"""Carido"""


[1]

Treatment

friedreich Ataxia (FA) a progressive neurological congenital disorder[2], wtih no treatment identified only possible pharmaceutics which can reduce the progression of FA however not significantly. Whereas significant treatment poties of FA or reduction in progression are the following:

  • Iron-chelation
    • deferoxamine
  • Antioxidants:
    • Idebenone
    • Coenzyme Q10

Q10 an electron carrier of reduction of oxidative stress with the combination of vitamin E, combination of Q10 and vitamin E displayed a positive effect[3]. Where Q10 and vitamin E conveyed the cardiac and skeletal improvement with the betterment of the mitochondrial synthesis[4].

  1. <pubmed>19283344</pubmed>
  2. <pubmed>19283349</pubmed>
  3. <pubmed>19049556</pubmed>
  4. <pubmed>15824263</pubmed>