Difference between revisions of "User:Z5177691"

From Embryology
 
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[[Student Page]]
 
[[Student Page]]
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[https://www.ncbi.nlm.nih.gov/pubmed/ PubMed]
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[[File:Chicken embryo E-cad and P-cad gastrulation.png|500px]]
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==Search Databases==
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[http://www.ncbi.nlm.nih.gov/sites/gquery?term=embryo ''embryo'']
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<pubmed>28786202</pubmed>
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[http://www.ncbi.nlm.nih.gov/sites/gquery?term=notochord ''notochord'']
  
 
====Belbin Model Team Roles====
 
====Belbin Model Team Roles====
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I thought it was interesting that both the sperm and the oocyte contain intracellular enzymes and organelles that affect the zona pellucida in different ways. The spermatozoa breaks down the zona pellucida through the acrosome reaction so that it can enter the oocyte and in response, the oocyte depolarizes and releases cortical granules onto the zona pellucida in order to make it impermeable to other sperm. These two reactions work in a way that only allows one sperm to fertilize the egg.   
 
I thought it was interesting that both the sperm and the oocyte contain intracellular enzymes and organelles that affect the zona pellucida in different ways. The spermatozoa breaks down the zona pellucida through the acrosome reaction so that it can enter the oocyte and in response, the oocyte depolarizes and releases cortical granules onto the zona pellucida in order to make it impermeable to other sperm. These two reactions work in a way that only allows one sperm to fertilize the egg.   
  
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==Peer Reviews==
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 +
'''Group 2''':
 +
Organization of the page is done really well, especially for Nephrogenesis and the different stages involved. There is a lot of good detail in each section, specifically the abnormalities section (it may help to break down the introduction of the abnormalities with an image however).  The subheadings included show a good knowledge of the topic and guide the reader through kidney development. Good support of ideas using helpful images and timeline table of kidney development. I think the page would be more complete if the current research, questions for the future, and general info on the renal system were complete.  Also, it may make more sense to put general information at the beginning to orient the reader (depending on what the “general info” entails).  Some animal models and examples of signals involved in the “Genes Expressed” section would also help complete the page.  For the images, there should be copyright information added, a description of the image, and the proper reference.
 +
 +
'''Group 3''':
 +
Great detailing of the development and signaling processes involved, it really showed me that the group had extensive knowledge on this topic.  In addition, there is a good balance of personal images (e.g. wnt signaling diagram) and web images which showed me that the group dedicated time to make sure the reader fully understood each aspect of the topic.  Most images also are properly cited with copyright statements, references, and description (some are missing, but overall are done well).  It was very helpful to include a glossary of terms at the end for the reader to refer to. An image for the cardiac looping steps would help to visualize steps. Information needs to be added for the notch pathway, sonic hedgehog, retinoic acid.  While the detail is very informative, there is a lot of information and can be a little overwhelming.  It might help to add more bullet points (with only essential information) or to edit some of the superfluous information. In addition, captions for the images would help so that the reader knows which image you’re referring to when referring to them in the text.
 +
 +
'''Group 4''':
 +
Anatomy of the adult eye is the shining feature of this page because it is very detailed and is balanced by personal images (one or two web images also might be helpful).  I like that the group used a lot of tables throughout the sections because it helps organize the essential information all into one--many need references however.  For example, the abnormalities section (fix spelling) is done very well; the table is well organized and nicely arranged so that the images are labeled at the bottom instead of interrupting the table itself.  Overall, there is a simple structure to the page that makes the page easy to read and it has a nice flow. There is missing information from stage 21-23 in the Carnegie stages table, as well as from parts of the eye components.  Development of the eye components is informative but could be improved by adding visuals in each section.  While there is a lot of helpful detail for overall eye anatomy, some information on signaling, current research, future questions and animal models would make it better. An introduction would also be beneficial. 
 +
 +
'''Group 5''':
 +
Lung histology and cardiovascular  are beautifully drawn but maybe the terms could be bolded because it is a little hard to fully make out the labels on the diagrams.  I like that you guys integrated both the information and diagrams together by referring to them in the text instead of just planting the image there without referring to it.  It makes the page enjoyable to read.  Also, referencing done throughout the abnormalities section is thorough and indicative of the extensive research done on it, good job. For the developmental timeline, it might help to move the pictures below the table--and label the images-- so that the table is only text and more easy to read all in one instead of having the images adding unnecessary spacing.  This may be a personal preference however.  For developmental signalling processes, both images containing information about FGF10 have the descriptions below them.  It might help to add that descriptions to the images themselves so that they don’t interrupt the flow of that section.  There is some information missing from current research, future questions, and glossary hat need to be completed as well.
 +
 +
'''Group 6''':
 +
This page seems to have the one of the best organizations.  All the sub headings needed for the project are included and completed (minus further questions). The introduction is a nice addition as it gives a roadmap to your page.  The entire Basic Anatomy is informative and sectioned nicely into the most important topics--some of the images may be a bit too large however.  I like that the information for the first and second trimester is separated, instead of clumping it all together.  Cerebellum development, cell signaling, and key historical discoveries have a lot of text and might need some diagrams or tables to break up the text.  Also it would help to put the key historical discoveries at the beginning so that the reader knows how it led to the information we know today. The neural development section should be moved below microanatomy and before early brain vesicles since it leads into that section. The
  
  

Latest revision as of 20:55, 11 October 2017

    2017 Project Groups
Group 1 Group 2 Group 3 Group 4 Group 5 Group 6

Z5177691

Z5178570

Z5093005

Z5059696

Z5059949

Z5178275

Z5178407

Z5076039

Z5017644

Z5015446

Z5178463

Z5076019

Z5059996

Z5076466

Z5018962

Z5177670

Z5117343

Z5075309

Z5075778

Z3416557

Z5178462

Z5059373

Z5114217

Z5062492

Z5076351

Z5177699

Z5113034

Z5114433

Z5076158

Z5018156

Mark Hill - Lab 1 page
Student Information (expand to read)  
Individual Assessments
Mark Hill.jpg

Please leave this template on top of your student page as I will add your assessment items here.

Beginning your online work - Working Online in this course

  1. Make your own page.
    1. Log-in to the embryology website using your student ID and Zpass.
    2. Click your student number (shown in red at the top right of the screen following log-in)
    3. Create page using the tab at the top of the page, and save.
  2. Add the following to the top of your page exactly as shown - {{ANAT2341Student2016}}
  3. How would you identify your Type in a group and add to your page.
  4. What was the most interesting thing you learnt in the fertilisation lecture?


If you have done the above correctly your ZID should be blue and not red on this page link - ANAT2341 2016 Students.


Here is the example page I made in Lab 1 Student Page. With a few more explanatory notes.

Click here to email Dr Mark Hill

Editing Links: Editing Basics | Images | Tables | Referencing | Journal Searches | Copyright | Font Colours | Virtual Slide Permalink | My Preferences | One Page Wiki Card | Printing | Movies | Language Translation | Student Movies | Using OpenOffice | Internet Browsers | Moodle | Navigation/Contribution | Term Link | Short URLs | 2018 Test Student
Lab 1 Assessment - Researching a Topic
In the lab I showed you how to find the PubMed reference database and search it using a topic word. Lab 1 assessment will be for you to use this to find a research reference on "fertilization" and write a brief summary of the main finding of the paper.
  1. Add a new Sub-heading "Lab 1 Assessment" (without the quotes).
  2. Search the database for a reference on "fertilisation" published in the last 5 years.
    1. It must be a research article not a Review.
    2. The full paper must be available online, not just the abstract.
  3. Add a link to this reference using its PMID using this code <pubmed>XXXXX</pubmed> replacing the Xs with just the PMID number (no text).
  4. Under the reference write a short summary of the papers main findings.
    1. Only 1-2 paragraphs.
    2. Must not be a copy of the paper abstract.
  5. Save and you are done.

PubMed logo.gif

Lab 2 Assessment - Uploading an Image
  1. Upload a research image using the guide information below. The image uploaded for your individual assessment can relate to your project or from fertilisation to week 3 of development (upload only a single image).
  2. Add that image to your own individual page (see Images) including an image title and its reference link.
  3. No two students should upload the same image, check new images before you upload.
  4. No student can delete an image once uploaded, please contact me by email with the image address and I will delete (with no penalty, just glad to help out).


2016 Group Project Topic - Signaling in Development

OK you are now in a group

  1. Go to the blank group page and add a topic that interests you along with your student signature.
  2. No two groups can do the same topic, but at this stage the final topic has not yet been decided (next week).

Initially the topic can be as specific or as broad as you want.


Chicken embryo E-cad and P-cad gastrulation.png

Chicken embryo E-cad and P-cad gastrulation[1]

References

  1. <pubmed>27097030</pubmed>
Lab 4 Assessment - GIT Quiz

ANAT2341 Quiz Example | Category:Quiz | ANAT2341 Student 2015 Quiz Questions |

Design 4 quiz questions based upon gastrointestinal tract. Add the quiz to your own page under Lab 4 assessment and provide a sub-sub-heading on the topic of the quiz.

An example is shown below (open this page in view code or edit mode). Note that it is not just how you ask the question, but also how you explain the correct answer.

Lab 5 Assessment - Course Review
Complete the course review questionnaire and add the fact you have completed to your student page.
Lab 6 Assessment - Cleft Lip and Palate
  1. Identify a known genetic mutation that is associated with cleft lip or palate.
  2. Identify a recent research article on this gene.
  3. How does this mutation affect developmental signalling in normal development.
Lab 7 Assessment - Muscular Dystrophy
  1. What is/are the dystrophin mutation(s)?
  2. What is the function of dystrophin?
  3. What other tissues/organs are affected by this disorder?
  4. What therapies exist for DMD?
  5. What animal models are available for muscular dystrophy?
Lab 8 Assessment - Quiz
A brief quiz was held in the practical class on urogenital development.
Lab 9 Assessment - Peer Assessment
  • This will form part of your individual assessment for the course.
  • Each student should now look at each of the other Group projects in the class.
  • Next prepare a critical assessment (should include both positive and negative issues) of each project using the project group assessment criteria.
  • This assessment should be pasted without signature on the top of the specific project's discussion page. (minimum length 3-5 paragraphs/project)
  • This critical assessment should also be pasted on your own student page.
  • Each student should therefore have 5 separate reports pasted on their own page for this assessment item.
  • Length, quality and accuracy of your reports will be part of the overall mark for this assessment.
    • there will be a greater loading on this than simple question assessments.
Lab 10 Assessment - Stem Cells
As part of the assessment for this course, you will give a 15 minutes journal club presentation in Lab 10. For this you will in your current student group discuss a recent (published after 2011) original research article (not a review!) on stem cell biology or technology.
Lab 10 - Stem Cell Presentations 2016
Group Mark Assessor General Comments

Group 1: 15/20

Group 2: 19/20

Group 3: 20/20

Group 4: 19/20

Group 5: 16/20

Group 6: 16/20

The students put great effort in their presentation and we heard a nice variety of studies in stem cell biology and regenerative medicine today. The interaction after the presentation was great.

As general feedback I would like to advise students to:

  • Never discuss M&M as a separate section in journal clubs. I gave this advice prior to the lab, but still most groups did talk through the M&M section.
  • Do not use your slides as cheat sheets, avoid text on slides, know what messages you need to get across, use images to illustrate these
  • Engage with your slides. Talk through them. Point at panels. Gauge your audience’s understanding by making eye contact with them
  • Avoid using abbreviations. Most people do not readily understand these and will lose track
Lab 11 Assessment - Heart Development
Read the following recent review article on heart repair and from the reference list identify a cited research article and write a brief summary of the paper's main findings. Then describe how the original research result was used in the review article.

<pubmed>26932668</pubmed>Development

ANAT2341Lectures - Textbook chapters  
Lecture (Timetable) Textbook - The Developing Human Textbook - Larsen's Human Embryology
Embryology Introduction Introduction to the Developing Human
Fertilization First Week of Human Development Gametogenesis, Fertilization, and First Week
Week 1 and 2 Second Week of Human Development Second Week: Becoming Bilaminar and Fully Implanting
Week 3 Third Week of Human Development Third Week: Becoming Trilaminar and Establishing Body Axes
Mesoderm Fourth to Eighth Weeks of Human Development Fourth Week: Forming the Embryo
Ectoderm Nervous System Development of the Central Nervous System
Early Vascular Cardiovascular System Development of the Vasculature
Placenta Placenta and Fetal Membranes Development of the Vasculature
Endoderm - GIT Alimentary System Development of the Gastrointestinal Tract
Respiratory Respiratory System Development of the Respiratory System and Body Cavities
Head Pharyngeal Apparatus, Face, and Neck Development of the Pharyngeal Apparatus and Face
Neural Crest Nervous System Development of the Peripheral Nervous System
Musculoskeletal Muscular System Development of the Musculoskeletal System
Limb Development of Limbs Development of the Limbs
Renal Urogenital System Development of the Urinary System
Genital Urogenital System Development of the Urinary System
Stem Cells
Integumentary Integumentary System Development of the Skin and Its Derivatives
Endocrine Covered through various chapters (see also alternate text), read head and neck, neural crest and renal chapters.
Endocrinology Textbook - Chapter Titles  
Nussey S. and Whitehead S. Endocrinology: An Integrated Approach (2001) Oxford: BIOS Scientific Publishers; ISBN-10: 1-85996-252-1.

Full Table of Contents

Heart Cardiovascular System Development of the Heart
Sensory Development of Eyes and Ears Development of the Eyes
Fetal Fetal Period Fetal Development and the Fetus as Patient
Birth and Revision
Additional Textbook Content - The following concepts also form part of the theory material covered throughout the course.
  1. Principles and Mechanisms of Morphogenesis and Dysmorphogenesis
  2. Common Signaling Pathways Used During Development
  3. Human Birth Defect
ANAT2341 Course Timetable  
Week (Mon) Lecture 1 (Mon 1-2pm) Lecture 2 (Tue 3-4pm) Practical (Fri 1-3pm)
Week 2 (1 Aug) Introduction Fertilization Lab 1
Week 3 (8 Aug) Week 1 and 2 Week 3 Lab 2
Week 4 (15 Aug) Mesoderm Ectoderm Lab 3
Week 5 (22 Aug) Early Vascular Placenta Lab 4
Week 6 (29 Aug) Gastrointestinal Respiratory Lab 5
Week 7 (5 Sep) Head Neural Crest Lab 6
Week 8 (12 Sep) Musculoskeletal Limb Development Lab 7
Week 9 (19 Sep) Renal Genital Lab 8
Mid-semester break
Week 10 (3 Oct) Public Holiday Stem Cells Lab 9
Week 11 (10 Oct) Integumentary Endocrine Lab 10
Week 12 (17 Oct) Heart Sensory Lab 11
Week 13 (24 Oct) Fetal Birth and Revision Lab 12

ANAT2341 2016: Moodle page | ECHO360 | Textbooks | Students 2016 | Projects 2016

Student Page

PubMed

Chicken embryo E-cad and P-cad gastrulation.png

Search Databases

embryo <pubmed>28786202</pubmed>

notochord

Belbin Model Team Roles

I would say I am a completer finisher because I am a perfectionist but, I am also an implementer because I plan ahead and do not like change especially if it "compromises efficiency or threatens well-established practices."

Fertilisation Lecture: What I found interesting

I thought it was interesting that both the sperm and the oocyte contain intracellular enzymes and organelles that affect the zona pellucida in different ways. The spermatozoa breaks down the zona pellucida through the acrosome reaction so that it can enter the oocyte and in response, the oocyte depolarizes and releases cortical granules onto the zona pellucida in order to make it impermeable to other sperm. These two reactions work in a way that only allows one sperm to fertilize the egg.

Peer Reviews

Group 2: Organization of the page is done really well, especially for Nephrogenesis and the different stages involved. There is a lot of good detail in each section, specifically the abnormalities section (it may help to break down the introduction of the abnormalities with an image however). The subheadings included show a good knowledge of the topic and guide the reader through kidney development. Good support of ideas using helpful images and timeline table of kidney development. I think the page would be more complete if the current research, questions for the future, and general info on the renal system were complete. Also, it may make more sense to put general information at the beginning to orient the reader (depending on what the “general info” entails). Some animal models and examples of signals involved in the “Genes Expressed” section would also help complete the page. For the images, there should be copyright information added, a description of the image, and the proper reference.

Group 3: Great detailing of the development and signaling processes involved, it really showed me that the group had extensive knowledge on this topic. In addition, there is a good balance of personal images (e.g. wnt signaling diagram) and web images which showed me that the group dedicated time to make sure the reader fully understood each aspect of the topic. Most images also are properly cited with copyright statements, references, and description (some are missing, but overall are done well). It was very helpful to include a glossary of terms at the end for the reader to refer to. An image for the cardiac looping steps would help to visualize steps. Information needs to be added for the notch pathway, sonic hedgehog, retinoic acid. While the detail is very informative, there is a lot of information and can be a little overwhelming. It might help to add more bullet points (with only essential information) or to edit some of the superfluous information. In addition, captions for the images would help so that the reader knows which image you’re referring to when referring to them in the text.

Group 4: Anatomy of the adult eye is the shining feature of this page because it is very detailed and is balanced by personal images (one or two web images also might be helpful). I like that the group used a lot of tables throughout the sections because it helps organize the essential information all into one--many need references however. For example, the abnormalities section (fix spelling) is done very well; the table is well organized and nicely arranged so that the images are labeled at the bottom instead of interrupting the table itself. Overall, there is a simple structure to the page that makes the page easy to read and it has a nice flow. There is missing information from stage 21-23 in the Carnegie stages table, as well as from parts of the eye components. Development of the eye components is informative but could be improved by adding visuals in each section. While there is a lot of helpful detail for overall eye anatomy, some information on signaling, current research, future questions and animal models would make it better. An introduction would also be beneficial.

Group 5: Lung histology and cardiovascular are beautifully drawn but maybe the terms could be bolded because it is a little hard to fully make out the labels on the diagrams. I like that you guys integrated both the information and diagrams together by referring to them in the text instead of just planting the image there without referring to it. It makes the page enjoyable to read. Also, referencing done throughout the abnormalities section is thorough and indicative of the extensive research done on it, good job. For the developmental timeline, it might help to move the pictures below the table--and label the images-- so that the table is only text and more easy to read all in one instead of having the images adding unnecessary spacing. This may be a personal preference however. For developmental signalling processes, both images containing information about FGF10 have the descriptions below them. It might help to add that descriptions to the images themselves so that they don’t interrupt the flow of that section. There is some information missing from current research, future questions, and glossary hat need to be completed as well.

Group 6: This page seems to have the one of the best organizations. All the sub headings needed for the project are included and completed (minus further questions). The introduction is a nice addition as it gives a roadmap to your page. The entire Basic Anatomy is informative and sectioned nicely into the most important topics--some of the images may be a bit too large however. I like that the information for the first and second trimester is separated, instead of clumping it all together. Cerebellum development, cell signaling, and key historical discoveries have a lot of text and might need some diagrams or tables to break up the text. Also it would help to put the key historical discoveries at the beginning so that the reader knows how it led to the information we know today. The neural development section should be moved below microanatomy and before early brain vesicles since it leads into that section. The



Here is the Student Page demonstration page I showed in the Practical class.

Use this page to practice editing and don't forget to add a topic to the 2017 Group Project 1 page.



 2017 ANAT2341 - Timetable | Course Outline | Group Projects | Moodle | Tutorial 1 | Tutorial 2 | Tutorial 3

Labs: 1 Fertility and IVF | 2 ES Cells to Genome Editing | 3 Preimplantation and Early Implantation | 4 Reproductive Technology Revolution | 5 Cardiac and Vascular Development | 6 CRISPR-Cas9 | 7 Somitogenesis and Vertebral Malformation | 8 Organogenesis | 9 Genetic Disorders | 10 Melanocytes | 11 Stem Cells | 12 Group

Lectures: 1 Introduction | 2 Fertilization | 3 Week 1/2 | 4 Week 3 | 5 Ectoderm | 6 Placenta | 7 Mesoderm | 8 Endoderm | 9 Research Technology | 10 Cardiovascular | 11 Respiratory | 12 Neural crest | 13 Head | 14 Musculoskeletal | 15 Limb | 16 Renal | 17 Genital | 18 Endocrine | 19 Sensory | 20 Fetal | 21 Integumentary | 22 Birth | 23 Stem cells | 24 Revision

 Student Projects: 1 Cortex | 2 Kidney | 3 Heart | 4 Eye | 5 Lung | 6 Cerebellum