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Summary of Article I: <ref><pubmed>26193891</pubmed></ref>
Summary of Article I: <ref><pubmed>26193891</pubmed></ref>
PMID 26193891
PMID 26193891



Revision as of 17:26, 13 August 2015

--Mark Hill (talk) 17:16, 5 August 2015 (AEST) Well done, you were first! We will be talking more about this in the Practical on Friday.

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Lab Attendance

--Z5088434 (talk) 13:46, 7 August 2015 (AEST)

Test student 2015

Lab 1 - Online Assessment

Summary of Article I: [1]

PMID 26193891

The aim of the prospective, self-controlled study was to investigate the impact of low-dose growth hormone (GH) supplementation for patients undergoing in vitro fertilization (IVF) with poor ovarian response (POR), which is defined as IVF incidence rates between 9 and 24%. GH is known to participate in follicular development by regulating gonadotropins in granulosa cells which in turn regulate the synthesis of IGF-I. This growth factor plays a major role in the synthesis of sex steroids and, thus, oocyte maturation. GH has been administered to POR patients since the 1990s, however, with mixed results. Therapeutic advantages were only established in women of advanced reproductive age. A possible reason for this unsuccessful administration is proposed to be the GH dose; the majority of doses used for POR patients is equal to those used in patients with GH-deficiency. However, POR patients are usually not GH-deficient, which leads to the investigation of the effects of lower dose GH supplementation to POR patients.


Method:


Results:

References

PMID 26193891

  1. <pubmed>26193891</pubmed>