Lab 1 --Z3374173 11:49, 25 July 2012 (EST)
Lab 2 --Z3374173 10:05, 1 August 2012 (EST)
Lab 3 --Z3374173 10:09, 8 August 2012 (EST)
Lab 1 Assessment
The first successful In Vitro Fertilisation occured in 1973, at Monash University, though it lasted only a few days. In 1977 the first IVF baby would be conceived, with Louise Brown as the first human ever to be born using the method of IVF in 1978. Later on in years Robert G. Edwards was awarded the Nobel Prize in Physiology or Medicine with his development of the technology.
Improved implantation and ongoing pregnancy rates after single-embryo transfer with an optimized protocol for in vitro oocyte maturation in women with polycystic ovaries and polycystic ovary syndrome
This paper's objectives was to find an optimal way for oocyte in vitro maturation that would improve the implantation and successfulness of the pregnancy for women that have/had Polycyctic Ovary Syndrome. Using FSH priming, larger sized follicles, hormone therapy and blastocyst stage transfers, they found that the maturation and implantation rates were improved compared to that of previous studies, and that it compares to that of IVF of women without Polycyctic Ovary Syndrome. 29 pregnancies were resultant of the IVM and 28 live births occurred. There was one loss as it was an ectopic pregnacy, and there was no congenital birth defects.  Journal Article
Lab 2 Assessment
Oct-4 is a protein that is important for pre-implantation development as well as being a necessary part in endoderm formation. Without Oct-4 the endoderm would not form properly and cause problematic repercussions. 
Lab 3 Assessment
Gestational age is a term most commonly used to describe at how far along the pregnancy is. This is usually determined by measuring the size of the thigh, head and abdomen of the fetus. Described from the first day of last menstrual cycle to the current date in weeks.  This compared to Post-fertilization age which describes the approximate point at which the ovum was fertilized. Usually it occurs two weeks after the menstrual period and is calculated by deducting two weeks off the Gestational age. Gestational age is used in clinical areas because it is measured by size of limbs and development of the fetus, this would allow a better understanding of the development of the fetus but also the development of the placenta and surrounding tissues. As the Gestational stage is measured from the first day of the last menstrual cycle, the whole process of the ovum being released from the ovary as well as fertilized is included within the age, as is the cycles of the endometrium of the uterus. Rather than having an age that excludes these important processes that happen for total conception.
- Stephen M. Junk, Ph.D., Doreen Yeap, M.B.B.S., F.R.A.N.Z.C.O.G. Improved implantation and ongoing pregnancy rates after single-embryo transfer with an optimized protocol for in vitro oocyte maturation in women with polycystic ovaries and polycystic ovary syndrome Fertility and Sterility: 2012 Journal Article
- Szczepańska K, Stańczuk L, Maleszewski M. Oct4 protein remains in trophectoderm until late stages of mouse blastocyst development. Reproductive Biology:2011 Jul;11(2):145-56. Article
- Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Gestational age Medline Plus