Difference between revisions of "User:Z3374116"

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{{StudentPage2014}}
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 17:18, 5 August 2015 (AEST) Note your student number is already blue, as you have been previously enrolled in this course.
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Resource Investigator
  
 
==Lab Attendance==
 
==Lab Attendance==
Lab2 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 11:17, 13 August 2014 [EST]
 
  
Lab3 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 11:06, 20 August 2014 (EST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 13:45, 7 August 2015 (AEST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:12, 14 August 2015 (AEST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:08, 21 August 2015 (AEST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:03, 4 September 2015 (AEST) - Left early for Funeral
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:16, 11 September 2015 (AEST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:26, 18 September 2015 (AEST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:44, 25 September 2015 (AEST)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:13, 9 October 2015 (AEDT)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:35, 16 October 2015 (AEDT)
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--[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 23 October 2015 - Attendance did not log properly (heart formation lab where you went though our projects and said it was too pink)
  
Lab4 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 11:10, 27 August 2014 (EST)
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==Lab Assessment 1==
  
Lab5 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 11:17, 3 September 2014 (EST)
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'''Article 1'''
  
Lab6 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 11:32, 10 September 2014 (EST)
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<pubmed>26260201</pubmed>
  
Lab7 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:08, 17 September 2014 (EST)
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This article was written in aims to evaluate a prospectively implemented clinical algorithm which served in the early identifications of Ectopic pregnancy (EP) and Heterotopic pregnancy (HP) after use of assisted reproductive technologies (In-vitro fertilization). The data used in this research were patients who all received in-vitro fertilization or other methods of Assisted reproductive technology from between January 1995 to June 2013.
  
Lab8 --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 11:29, 24 September 2014 (EST)
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The early pregnancy stage was monitored using clinical algorithms where all pregnancies were screened using Human chorionic gonadotropin (hCG) levels and any reported symptoms during pregnancy as well as use of ultrasound evaluations where hCG levels were abnormal or patient reported any pains.
  
Lab9 (8/10/2014) --[[User:Z3374116|Z3374116]] ([[User talk:Z3374116|talk]]) 12:41, 8 October 2014 (EST)
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The research found that within the 3904 pregnancies included in the data, the incidence of Ectopic and Heterotopic pregnancies were 0.77% and 0.46% respectively. The clinical algorithm managed to detect and select 96.7% of the 0.77% diagnosed with EP as well as 83.3% of the 0.46% diagnosed with HP leading to earlier treatment and resolution of the problem. These results showed the effectiveness of the developed clinical algorithm in the early identification and prompt intervention of EP and HP bypassing the catastrophic morbidity associated with delayed diagnosis
  
http://www.ncbi.nlm.nih.gov/pubmeb
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'''Article 2'''
  
[http://www.ncbi.nlm.nih.gov/pubmed PubMed]
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<pubmed>24939956</pubmed>
  
[http://www.ncbi.nlm.nih.gov/pubmed/25084016 PMID25084016]
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The article researched the effects of different levels of progesterone on the day of human gonadotropin administration in the live birth delivery rates during in-vitro fertilization. Previous researches have shown that the presence of late follicular phase progesterone is essential for follicular development, ovulation and endometrial receptivity. Studies were carried out on 2723 cycles performed in patients aged between 19 ~35 years of age and undergoing controlled ovarian stimulation.
  
<pubmed>25084016</pubmed>
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The patients underwent ovarian stimulation using a gonadotropin releasing hormone antagonist for pituitary down-regulation and then final oocyte maturation was triggered using hCG 36h before oocyte retrieval. On the day of hCG administration, progesterone evaluation was performed and live birth delivery rates were compared at regular progesterone intervals.
  
==Lab Assessment 1 - Fertilization References==
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The study found that live birth rates were significantly lower in patients with bow low (<0.5 ng/ml) and high (>1.5 ng/ml) late follicular progesterone levels.
# Predictive factors in in vitro fertilization(IVF): a systematic review and meta-analysis
 
      *http://humupd.oxfordjournals.org/content/16/6/577.full.pdf+html
 
  
Article focused on acquiring data from previous case studies and research papers, collaborating data to determine the success rate of pregnancy prior In-vitro fertilization and certain factors which play a part in a successful pregnancy from the procedure.
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 11:09, 4 September 2015 (AEST) These are good summaries of the 2 papers with correct reference format. (5/5)
  
===Method===
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== Lab Assessment 2 ==
The articles which were used in the data pooling were eligible to be used if they evaluated the association between one or more of the pre-identified factors (listed below) and its effect on pregnancy after the use of IVF in an unselected patient group and were not considered if they reported on a specific patient group within the sub fertile IVF population or if no association was drawn between eh predictive factors and pregnancy or could not be determined.
 
From the data the following factors were carefully analysed to determine if they play a part in the success rate of pregnancy post IVF; Age, Type of Infertility, Duration of Infertility, Basal Follicle stimulating hormones, Oocytes present, Fertilization method and Embryo Quality
 
===Results===
 
From the 14 studies that were used in the data pooling, it was found that ‘women aged 35 years or older had significantly lower pregnancy chances compared with women who were younger than 25’ (Loendersloot et al., 2010) as well as studies showing that women who were aged above 30, in comparison to those in their mid-twenties had a lower chance of pregnancy. Age was recognised as a ‘continuous variable’ throughout the studies which showed decreasing chances of a successful pregnancy as the patients age increases.
 
Further studies showed the relationship between the amount of bFSH (Basal Follicle Stimulating Hormones) and pregnancy. In 2 case studies, it was revealed that pregnancy chances were higher post IVF in patients with a lower level of FSH in comparison to women with a higher level of FSH concentration. Oddity Rates confirmed that ‘increasing bFSH values were associated with lower pregnancy rates after IVF’
 
3 of the studies determined the correlation of embryo quality to pregnancy after IVF.
 
It also found that women with embryos with higher development stage and morphology scores had higher pregnancy chances compared to those which scored lower and also, embryos which showed delayed or appropriate development stages had lower pregnancy chances compared to women with advanced development stages.
 
  
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[[File:Biopsy of Morula Stage Embryo.png|700px]]
  
--[[User:Z8600021|Mark Hill]] - There appears to be only a single article reviewed here? Your summary for this was correct and concise, though you have also not cited the reference correctly. (3/5).
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'''Biopsy of a Morula Stage Embryo'''<ref><pubmed>25191937</pubmed>|[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106433]</ref>
  
== Lab Assesment 2 - Uploading a Research Image==
 
[[File:Immunofluroescent labelling of embryo for immunoreactive 5 - mehtylocytosine at different cell stages.png]]
 
  
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 11:10, 4 September 2015 (AEST) Image uploaded correctly with reference, copyright and student template. (5/5)
  
Immunofluroescent labelling of embryo for Immunoreactive 5 - Methylocytosine
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== Lab Assessment 3 ==
  
== Lab Assessment 3 - Project Researching==
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<pubmed>19573285</pubmed>
===Historical/Historic Finding for Neural Development===
 
<pubmed>19339620</pubmed>
 
<pubmed>17848161</pubmed>
 
<pubmed>8005032</pubmed>
 
<pubmed>9311417</pubmed>
 
<pubmed>12768653</pubmed>
 
  
== Lab Assesement 4 ==
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<pubmed>26190539</pubmed>
'''1. Identify a paper that uses cord stem cells therapeutically and write a brief (2-3 paragraph) description of the paper's findings.'''
 
  
<pubmed>23941289</pubmed>
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<pubmed>26246873</pubmed>
  
This study researched on the safety and efficacy of the use of human umbilical cord mesenchymal stem cells (UC-MSCs) for the treatment of rheumatoid arthritis (RA). A total of 172 patients who had been diagnosed with RA who were not recovering from use of traditional medication were chosen, then divided into two separate groups for different treatments, one group recieving disease-modifying anti-rheumatic drugs (DMARDs) plus medium without UC-MSCs and DMARDs with UC-MSCs via intravenous injection. Serum levels of inflammatiry chemokines.cytokines were measured and lymphocyte subsets in peripheral blood were analyzed. The serum levels of tumor necrosis factor-alpha and interleukin-6 decreased after the first UC-MSCs treatment (P<0.05). The percentage of CD4(+)CD25(+)Foxp3(+) regulatory T cells of peripheral blood was increased (P<0.05). The treatment induced a significant remission of disease.
 
  
The therapeutic effects maintained for 3-6 months without continuous administration, correlating with the increased percentage of regulatory T cells of peripheral blood. Repeated infusion after this period can enhance the therapeutic efficacy. In comparison, there were no such benefits observed in control group of DMARDS plus medium without UC-MSCs. In conclusion, there were no benefits recorded in the control group who recieved DMARDS plus medium withouth US-MSCs, indicating that treatments with DMARDs plus US-MSCs provides a safe, significant and persistent clinical benefit for patients with RA.
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 11:11, 4 September 2015 (AEST) These 3 references relate to your project topic. It would have been good to include even just a single sentence explaining why you selected these 3. (4/5)
  
'''2.There are a number of developmental vascular "shunts" present in the embryo, that are closed postnatally. Identify these shunts and their anatomical location.'''
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== Lab Assessment 4 - Quiz ==
  
3 developmental vascular ‘shunts’ are present in the embryo which are closed postnatally
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=== Mesoderm Development ===
 
1) Foramen Ovale
 
  
In the foetal stage, the Foramen Ovale is the opening in the inter-atrial septum which allows the blood to enter the left atrium from the right atrium. This opening closes at birth when lung gains function, the pulmonary pressure decreases and the left atrial pressure exceeds that of the right atrium, forcing the septum primum against the spectrum secundum closing the foramen ovale
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<quiz display=simple>
  
2) Ductus Venosus
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{Cells which migrate from '''somites''' form:
 +
|type="()"}
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- Respiratory System
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- Smooth Muscles
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- Digestive System
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+ Skeletal Muscles
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- Reproductive System
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|| '''Somites arise from the Paraxial Mesoderm and give rise to skeletal muscles as well as other musculoskeletal structures'''
  
In the foetus, the ductus venosus shunts blood from the left umbilical vein directly to the inferior vena cava and therefore allows oxygenated blood from the placenta to bypass the liverIt is critical in shunting oxygenated blood to the fetal brain. The remanent of the ductus venosus is found as ligamentum venosus attached to the left branch of the portal vein
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</quiz>
  
== Online photo submission for Group Project (Lab 8) ==
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=== Fertilization ===
[[Image:Arachnoid_cyst_with_hydrocephalus.jpg|350px]]
 
  
Arachnoid cyst with Hydrocephalus
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<quiz display=simple>
  
== Lab Assesment 7==
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{Which of the following statements are '''INCORRECT''' regarding Implantation?
'''1. Identify and write a brief description of the findings of a recent research paper on development of one of the endocrine organs covered in today's practical.'''
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|type="()"}
 +
- Implantation commences at day 6 ~ 7
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+ The blastocyst rolls along the uterine wall to align the inner cell mass furthest from the uterine epithelium
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- Implantation is the process in which a blastocyst enters the uterine wall
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- A coagulation plug forms where the blastocyst has entered the uterine wall
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|| '''The blastocyst initially rolls down the uterine walls aligning the inner cell mass to be closest to the uterine epithelium before implantation occurs. After the blastocyst has entered the Uterine wall, a coagulation plug forms at the site of implantation'''
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{At which of the following layers does Implantation occur?
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|type="()"}
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- Myometrium
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- Spongy layer of Endometrium
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- Perimetrium
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+ Compact layer of Endometrium
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- Implantation layer of Endometrium
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|| '''Implantation occurs in the Compact layer of Endometrium containing  dense stromal cells, uterine gland necks and capillaries of spiral arteries'''
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 +
</quiz>
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 11:12, 4 September 2015 (AEST) 3 questions here please. I will assess after the lab today.
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[[ANAT2341 Student 2015 Quiz Questions]]
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== Lab Assessment 5 ==
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'''What is the difference between Gastroschisis and Omphalocele?'''
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Omphalocele is fetal defect (occurring 1 in every 4000 births) which is defined as the herniation of the abdominal viscera into the umbilical cord. In this abdominal wall defect, internal abdominal organs such as the intestines, liver protrude outside of the belly via the belly button where the organs are covered by a thin, opaque sac which separates the internal organs with the fluids in the amniotic sac during pregnancy. The occurrence of Omphalocele is due to the incorrect or incomplete development of the muscles of the abdominal wall.
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Gastroschisis is a defect which is thought to have been caused due to the interruption of blood supply to the developing abdominal wall from the omphalomesenteric duct artery in the 8th week of gestation. Unlike Omphalocele occurring from the belly button, it is characterized by an extra-umbilical herniation of internal abdominal organs at the junction of umbilicus and normal skin (beside the belly button) and not enclosed in visceral peritoneum.  
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Omphalocele develops in the 9th week of development when the intestines do not re-enter the body cavity whereas Gastroschisis arises within the 6th ~ 7th week of development when the abdominal wall muscles of the baby do not develop properly
  
<pubmed>17986825</pubmed>
 
  
The journal focuses on the further understanding of genetic aetiology of some of the several forms of adrenal failures which can be present in childhood or infancy. Disorders which affect the adrenal development are termed 'adrenal hypoplasia'.
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'''<pubmed>2932813</pubmed>
 +
<pubmed>12130917</pubmed>
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<pubmed>15305094</pubmed>'''
  
Conditions occuring in the adrenal glands are grouped into:
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 12:45, 7 November 2015 (AEST) (4/5)
1) Secondary form of adrenal hypoplaisa due to panhypopituitarism / abnormality in ACTH synthesis
 
2) Adrenal hypoplasia as part of an ACTH resistance syndrome
 
3) Primary defects in the development of the adrenal gland itself
 
  
Adrenal hypoplasia is most commonly found occuring in X-linked form due to mutations in the nuclear receptor DAX1.
 
  
'''2. Identify the embryonic layers and tissues that contribute to the developing teeth.'''
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==Lab Assessment 7==
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'''1. Identify and write a brief description of the findings of a recent research paper on development of one of the endocrine organs covered in today's practical.'''
  
Teeth develop from the ectoderm and the endoderm. Enamel of teeth develops from the ectoderm of the oral cavity whereas all other tissues come from the assosicated mesenchyme. Development of teeth is in continuous stages
 
  
1) Dental lamina and bud stage - early in week 6 as U-shaped thickenings of the oral epithelium
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'''2. Identify the embryonic layers and tissues that contribute to the developing teeth.'''
  
2) Cap Stage - Deep surface of ectodermal tooth bud is invaginated by mesenchyme called 'dental papilla' which gives off 'dentin'. Ectodermal cap covering the papilla is called 'enamel organ' as it produces the future enamel of teeth
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Tooth development (Odontogenesis) begins in the 6th week of embryonic development and is made up of ectoderm, mesoderm and neural crest ectomesenchyme
  
3) Bell Stage - invagination of the enamel organ where the teeth forms the shape of a bell
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- '''Ameloblasts''': derived from the epithelium of ectoderm cells from the 1st pharyngeal arch which produces the enamel. Enamel covers the crown of the tooth and are only found to be present during the process of odontogenesis
  
== Lab Assesment 8 ==
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- '''Odontoblasts''': ectomesenchymal cells derived from the neural crest. These cells begin by forming the predentin which later hardens to become dentin
  
Basic Timeline for Gential Development
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 13:45, 7 November 2015 (AEST) Only the tooth has been described, not the endocrine development. (2/5)
  
Week 3-4: Migration of primordial germ cells during gastrulation
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==Peer Reviews==
  
Week 4: Intermdiate mesoderm and pronephros primordium
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'''Group 1'''
  
Week 5: Mesonephros and mesonephric duct
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From first glance of the page, just by looking at the contents table found at the top of the wikipage, I can already see that all the sections have been planned and well thought out with the appropriate subheadings and sub-subheadings which makes the page a lot easier to navigate if I were to be searching for something in particular on the topic ‘Three Person Embryo’
  
Week6: Ureteric bud, metanephros and Genital ridge
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The introduction is short and concise with the appropriate description of what the topic is about, adding the YouTube video in your introduction was a great touch (props to you for asking the maker permission to re-use as it’s under the YouTube Standard License) however I think this section could be improved by maybe addressing the key points that the wiki page will be covering
  
Week 7: Cloacal division, gonadal primordium (indifferent to 1st appearance of testis cords)
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It’s great to see some history behind the development and progression of ‘Mitochondrial’ Donation throughout the years!! Is there any more history regarding this topic or is 1997 the first date with historical records?? Tabulation of the data may clean up this section, but otherwise great find!
  
Week 8: Paramesonephric duct, clear gonadal differentiation
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Under the benefits section, no actual benefits seems to have been listed? I think this section has not yet been completed
  
The differentiation of gonads into testis or ovaries depends only on the chromosomes received from the parents, either the X chromosomes for females and Y chromosome for males. Expression of SRY protein encodes 204 amino acid protein, the transcription factors bind to specific sites of DNA and regulates the transcription of other genes.
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The pictures and information under the ‘Technical Progression’ subheading is substantial and informative. The images seem to have been referenced and labelled accordingly but not sure if they are reusable as the sites / locations you obtained them from do not mention permission rights for reuse of their material. Some of the referencing done still shows the blue PMID which disrupts the flow of the project page.
  
In males, the SRY is expressed in the primordia of support cells which surround germ cells, transforming the support cells into much needed Sertoli cells. Sertoli cells instigate the germ cells and steroid secreting cells to undertake a male development pathway
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It is clear that a lot of research has been done into making this page what it is currently. I would suggest firstly to check that all material used on your page is re-useable as well as fixing up the minor coding of references and also grammar and spelling mistakes throughout the page. Great work!!
  
In the male gonad, the paramesonephric dict degenerates due to the introduction of anti-mullerian hormone which is secreted by sertoli cells, mesonephric duct is maintained and differentiates under the influence of testosterone, they extend out of the gonad to form the ductus deferens
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'''Group 3'''
  
[[Image:Bailey309.jpg|350px]]
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Straight away I was impressed by the images and the table of contents. It appears that all subheadings are relevant and well planned. Having the definition in the introduction was great as well as the addition of epidemiology including the map, however I think it would be much more informative for readers if you touched on the variety of topics your wikipage will be covering (if they did not bother to read the table of contents)
Image representing certain persistent portions of mesonephros in the male
 
  
== Lab Asssesment 9 ==
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The variety of causes which are mentioned for Female infertility was concise and very informative under their respective sub-subheadings and with the appropriate referencing. There is a substantial amount of information provided under the ‘Pathogenesis’ section which clearly defines the different types, however, it seems that rather than Female infertility you have focused more information on ‘PCOS’ rather than all round? The images added in this heading was great in breaking up the text and the addition of animal and cell culture models were a really nice addition
  
***Group 1***
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The signs and symptoms section is nice and simple while giving the reader all the necessary information without lines and lines of text which makes the information easy to access however in a section of ‘Diagnosis’, I think use of paragraphing may help the reader take rests to understand the large amount of information provided in the blood testing, maybe make use of a glossary for the bolded words. Other than that the image has been reference properly and the subheadings were helpful
The group project has covered a wide angle of the fetal development of Respiratory system. The introduction is very concise and informative, but it would have been better to give us a heads up of what is going to be included in the wiki-page. The different histological diagrams of 'respiratory zones' were good in giving us an idea of what the cells look like, however, none of the diagrams are labelled leaving us to our own imagination of what is what (I'm guessing the first picture in the project represents a zone of respiratory cells?)
 
  
The tabulated data makes it easier to understand the different stages of development, splitting it into different stages (including the weeks underneath), I think it would be better to maybe condense the information in the table to key dot points as currently it seems saturated with information. Maybe even include histological diagrams of the different development stages
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The tabulated information in Prevention and Treatment was a great way to avoid walls and walls of text as some of the other groups have done clearly identifying the cons of certain ‘current’ treatment methods. The amount of references that went into making this wikipage is a clear indication of how much effort was put in to making this page what it is
  
There are no current models listed in the 'Current Research, Models and Findings' section but there has been extensive research in the Research and Findings. The information in this section is very well laid out allowing easy reading and understanding of the information that has been presented. The diagram used at the end of this subsection is very simple and informative :)
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Great job on the project so far!! Only thing I can say is to try look for a video regarding Female infertility!! Good luck!
  
In the 'Conducting System' - the picture does not appear for me (only me?)
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'''Group 4'''
  
Historical findings have also been extensively covered, a well put out timeline with different observation timepoints. Abnormalities have also been extensively covered in the group project, however I think it would be better to employ the use of more diagrams of the different diseases and abnormalities.
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I would like to say great work of find substantial information and images to go along with your wikipage. From the table of contents there seems to be a lot of topics being addressed and with your use of subheadings, it makes navigating the page much easier. The short introduction described the basic meaning of male infertility well as well as the inclusion of some basic statistics is a nice bit of information however it would be nice to have some information regarding what your wikipage will be covering in general
  
Having the references scattered throughout the page seems to break the flow of the group project :/ Maybe have them all grouped up under a separate subheading :)
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The background information is very useless as it provides the reader with some basic knowledge of where the male reproductive system and its components come into play in regard to the topic of male infertility. The images used are all referenced appropriately and assists in understanding where each component is located and what they look like. The tabulated data of the different types of male infertility allows the readers to easily understand the different kinds and what their relative symptoms are easily. Good job on that! The use of video is nice to see, it has relevance to your topic.
  
Great work on your project, a little touch up here and there with some more diagrams will greatly improve this project
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Regarding information within the section ‘Major Causes of Infertility’, the information provided is awesome, however there just seems to be too much information crammed into small paragraphs which makes it quite draining to read. There are many terms which some readers may not know or understand, so I recommend using a glossary to help sort this problem out  maybe simplify the information (if you can)  or break up into more paragraphs to make it easier to read and digest. There are some sections which have no information, however I know that these will be filled by the submission date. The large amount of references is indicative of how much work went into the wikipage for your group!
  
***Group 2***
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Good work guys!!
The introduction to this group project is informative and explains the basic components and function of the Renal system. It gives us a nice overview of the whole project . Historical section needs to have information put it? (maybe tabulated data or a timeline structure?)
 
  
Developmental timeline is laid out simply and basic information which is good for the average readers but not so helpful when it comes to someone who has no idea what the words mean (from an outside point of view) maybe even tabulate the data to clean it up a bit and make it look formal as well as putting in diagrams of the different developmental stages of Renal.
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''' Group 5 '''
  
The current research model has a interesting article view added however, it just seems like a condensed wall of words, maybe lay out the section in a way to help readers read the text easily? Its really hard to keep track. Interesting diagram used :) Maybe add more current research papers, more citations? (just a suggestion)
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Great work so far on your wikipage guys, even just at first glance it is clear how much research and work was put in to make this page what it is. The amount of information that has been provided on the page is quite substantial. Within the contents table at the top of the page, each section has been broken down accordingly allowing ease of navigation for those who wish to know more about Oncofertility. The introduction provides us with a nice description of what Oncofertility is as well as a definition of the term ‘infertility’ which is helpful to those who do not know much information regarding the terms
  
The section with the subheadings of kidney, ureter and bladder is extremely well explained with appropriate diagrams included throughout the descriptions! However it would also be better to split up certain parts of the text as, like the current research model section, it is hard to keep up.
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I think that some information can be split up into more paragraphs, especially information in the subheading ‘Radiation’, currently it is just a wall of text which makes it extremely hard to focus and understand all the words. Seeing as it is a procedure, maybe someone can include a hand-drawn image of the process and how affects the body?
  
Maybe include more Renal abnormalities in your group project, the ones listed are interesting and some have diagrams to follow on with them, but some of them have just the basic information and nothing else. More diagrams and more information on the abnoralities you have put would greatly help in the project structure.
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Information in the other sections are well organised and provides useful relevant information as well as providing deeper knowledge into certain techniques, chemicals and cancer cells in general. The information is a good addition (for both cancer cells and chemotherapy  however there is no referencing available to be found for both your videos. I think more images (hand-drawn or from other resources) need to be added to balance out the amount of text you have on your page.
  
For referencing, the scattered references throughout the project interrupt with the flow of the project, maybe put all the references in a separate subheading at the bottom of the wiki-page to help with looks :)
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The overall structure other than the main subheadings that you currently have could be improved as some sections are just too long and cover a too broad information to be just kept under one subheading. Make use of more dot points to summarise the information. The table under Fertility preservation in women was concise and provides easy to read data, however the colouring of the background makes it hard to distinguish where each section of the box finishes and ends (maybe I’m colour-blind). I also think that it might be helpful to add a glossary to the bottom of your wikipage as there are quite a lot of terms that people may not understand 
  
Overall great work, some touch-ups to structure and visual aesthetics and you should be good :)
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Overall great work on your wikipage, I look forward to reading the final version!! Good luck!
  
***Group 5***
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'''Group 6'''
A clear and concise introduction to the group project allows us to know what to expect to see throughout the group project. It clearly outlines what will be covered.
 
  
The development overview section is really well laid out, with information split up by breaks to allow for easier reading and for readers to recognize the different stages of development. The tabulated data, timeline and diagrams are extremely well put out! The information in the table description is adequate and explains what needs to be explained about the diagram (week 18 just says example?)
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Skimming through the page, it is clear that a lot of research has been done to make this page what it is, each subheading is well thought out (maybe a overdone a bit by the additional sub-subheadings) and allows a transition. However there is a crucial part of the page is missing, the introduction. By not having an introduction at the beginning of the page, the project just jumps straight into information giving no clues as to what the project will be covering overall. It would be nice to have a concise definition of Artificial Reproductive Technologies (maybe replace ‘ART’ for the full word for the wikipage heading) The history has some nice information, but I think it can be improved by making use of tables or a graph for each of the dates, or even dot points to break the constant text.
  
Recent findings section is nice a purple :) Informative and well broken down, however some more uses of paragraphing would help with the overall structure of this section. great use of diagrams with the recent findings. Last 2 Recent finding articles have yet to be explained right?
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Overall in the other sections, the pictures are nice and are references appropriately and the use of table is nice (might be a bit dark to see the writing clearly). I think that some of the information can be broken up into small paragraphs rather than having one paragraph with around 30~40 sentences as it breaks down the information into easily digestible parts considering the amount of information which has been provided.  
  
Historical findings have been covered with lots of good information, use some use of text formatting (bolding words) to help with the different sub-subheadings in this section :) Some in-text citations would be helpful in understanding where the information came from.
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The advantages and disadvantages of ART have been mentioned clearly without using lots of text, it makes the information easy to understand. I also think that more images are needed considering the widespread nature of the topic you have chosen, maybe some hand drawn images for those which you cannot find copyright information or a video to explain some of the procedures. Some grammar and formatting should be done before final submission to ensure that all sections are uniform in their font and sizing.
  
Abnormalities have been extensively covered with some interesting information and nice use of diagrams as well as the descriptive text which accompany them. Adding a few more abnormalities and diagrams would help with the project :)
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Great work on finding all the information and making this page so far!! Good luck
  
Overall great work on your group project! Looking very good so far! Fix up some citation errors and place all your references at the bottom of the page and you should be all set to go
 
  
***Group 6***
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 13:45, 7 November 2015 (AEST) (17/20)
There is currently no information under the 'introduction' subheading? With no introduction, we arn't given the basic outline of what systems will be covered as well as basic understanding of what the endocrine system comprises of and what its basic functions in our body are. Maybe put up this information when you guys have the chance to as it could help out with the flow of the group project.
 
  
There is nice information on the different parts of the Endocrine system (a typo for 'abnormalities' in the Pineal Gland section) but no in-text citations as of now, it would greatly clarify where the information came from as well as save you from having all the references under your body of text in that subheading :)
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== Lab Assessment ==
  
Under Hypothalamus subheading, the table is not complete yet, but once filled in would look great. Maybe even put the tables description in bold (yes I saw the text above it) Good use of diagrams throughout the project.
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'''[https://embryology.med.unsw.edu.au/embryology/Slides/Embryo_Stages/Stage22/08-eye/Stage22-08-eye.html?zoom=5&lat=-2259.81863&lon=4843.06006&layers=B Cillary Body]'''
  
Although all the different parts of the system are thoroughly covered, there is no information no subheading which marks Current research models and findings as well as Historical findings? It might be good to add such information into the group project as they are two of the main subheadings Mark put out for us on the initial assignment release :)
+
The cillary body is the section of the eye which houses the cillary muscle, which works to control the shape of the lens, and also the cillary epithelium, which produces the aqueous humor. It is a circular thickening of the walls within the eyes which divides the vitreous body from the posterior chamber. The inner layer is transparent and continuous with the neural tissues of the retina whilst the outer layer is highly pigmented and runs continuous with the retinal pigment epithelium and forms the cells of the dilator muscle.
  
Also for the references, place all the references in the subheading you guys have made at the bottom of the page as well as putting in-text citations to help with the overall flow of the group project.
+
'''Embryology Link''' [[Vision - Retina Development#Retinal Pigment Epithelium]]
  
Great job overall, there is loads and loads of information on this system and its clear you guys are doing it well so far!
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 13:45, 7 November 2015 (AEST) (5/5)
 +
==References==
 +
<pubmed>26244658</pubmed>
 +
Look at this aye <ref><pubmed>26244657</pubmed></ref>
  
***Group 8***
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<References/>
The introduction to your page is extremely funny, but this is completely irrelevant to the project and should be taken out before you submit the assignment. There are long blocks of texts on the page, with no tables or any pictures sadly. There should be a some images/digarams/videos for each heading. There is a number of good headings, with information within that needs to be further developed. There is great potential for this group project to develop further.
 
  
There is a Heading labelled, 'Muscle development general timeline' however, underneath this section, there is only a small paragraph with no timeline whatsoever. If you don't want to have a timeline in this section of your project, then remove the word 'timeline from this heading'. However, I think a timeline would be a great way to show an overview of the key events of the muscoskeletal system.
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 13:45, 7 November 2015 (AEST) Stem Cell Presentation (17/20)
  
There is an broad, and long section of information under "background embryonic development". Just remember that our projects are about fetal development and not the embryonic stage of the system our project is about. The time spent on writing this section could have been spent on working on other parts of the assignment that require greater attention.
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--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 20:42, 3 November 2015 (AEDT) CATEI submitted (5)
  
Towards the end of the references list, there are references that have not properly been citied. There also exists a format error in your reference list that would need to be fixed before the final group submission.
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[[Test student 2015]]
 +
{{StudentPage2015}}

Latest revision as of 11:04, 11 November 2015

--Mark Hill (talk) 17:18, 5 August 2015 (AEST) Note your student number is already blue, as you have been previously enrolled in this course.

Resource Investigator

Lab Attendance

--Z3374116 (talk) 13:45, 7 August 2015 (AEST)

--Z3374116 (talk) 12:12, 14 August 2015 (AEST)

--Z3374116 (talk) 12:08, 21 August 2015 (AEST)

--Z3374116 (talk) 12:03, 4 September 2015 (AEST) - Left early for Funeral

--Z3374116 (talk) 12:16, 11 September 2015 (AEST)

--Z3374116 (talk) 12:26, 18 September 2015 (AEST)

--Z3374116 (talk) 12:44, 25 September 2015 (AEST)

--Z3374116 (talk) 12:13, 9 October 2015 (AEDT)

--Z3374116 (talk) 12:35, 16 October 2015 (AEDT)

--Z3374116 (talk) 23 October 2015 - Attendance did not log properly (heart formation lab where you went though our projects and said it was too pink)

Lab Assessment 1

Article 1

<pubmed>26260201</pubmed>

This article was written in aims to evaluate a prospectively implemented clinical algorithm which served in the early identifications of Ectopic pregnancy (EP) and Heterotopic pregnancy (HP) after use of assisted reproductive technologies (In-vitro fertilization). The data used in this research were patients who all received in-vitro fertilization or other methods of Assisted reproductive technology from between January 1995 to June 2013.

The early pregnancy stage was monitored using clinical algorithms where all pregnancies were screened using Human chorionic gonadotropin (hCG) levels and any reported symptoms during pregnancy as well as use of ultrasound evaluations where hCG levels were abnormal or patient reported any pains.

The research found that within the 3904 pregnancies included in the data, the incidence of Ectopic and Heterotopic pregnancies were 0.77% and 0.46% respectively. The clinical algorithm managed to detect and select 96.7% of the 0.77% diagnosed with EP as well as 83.3% of the 0.46% diagnosed with HP leading to earlier treatment and resolution of the problem. These results showed the effectiveness of the developed clinical algorithm in the early identification and prompt intervention of EP and HP bypassing the catastrophic morbidity associated with delayed diagnosis

Article 2

<pubmed>24939956</pubmed>

The article researched the effects of different levels of progesterone on the day of human gonadotropin administration in the live birth delivery rates during in-vitro fertilization. Previous researches have shown that the presence of late follicular phase progesterone is essential for follicular development, ovulation and endometrial receptivity. Studies were carried out on 2723 cycles performed in patients aged between 19 ~35 years of age and undergoing controlled ovarian stimulation.

The patients underwent ovarian stimulation using a gonadotropin releasing hormone antagonist for pituitary down-regulation and then final oocyte maturation was triggered using hCG 36h before oocyte retrieval. On the day of hCG administration, progesterone evaluation was performed and live birth delivery rates were compared at regular progesterone intervals.

The study found that live birth rates were significantly lower in patients with bow low (<0.5 ng/ml) and high (>1.5 ng/ml) late follicular progesterone levels.

--Mark Hill (talk) 11:09, 4 September 2015 (AEST) These are good summaries of the 2 papers with correct reference format. (5/5)

Lab Assessment 2

Biopsy of Morula Stage Embryo.png

Biopsy of a Morula Stage Embryo[1]


--Mark Hill (talk) 11:10, 4 September 2015 (AEST) Image uploaded correctly with reference, copyright and student template. (5/5)

Lab Assessment 3

<pubmed>19573285</pubmed>

<pubmed>26190539</pubmed>

<pubmed>26246873</pubmed>


--Mark Hill (talk) 11:11, 4 September 2015 (AEST) These 3 references relate to your project topic. It would have been good to include even just a single sentence explaining why you selected these 3. (4/5)

Lab Assessment 4 - Quiz

Mesoderm Development

Cells which migrate from somites form:

Respiratory System
Smooth Muscles
Digestive System
Skeletal Muscles
Reproductive System


Fertilization

1

Which of the following statements are INCORRECT regarding Implantation?

Implantation commences at day 6 ~ 7
The blastocyst rolls along the uterine wall to align the inner cell mass furthest from the uterine epithelium
Implantation is the process in which a blastocyst enters the uterine wall
A coagulation plug forms where the blastocyst has entered the uterine wall

2

At which of the following layers does Implantation occur?

Myometrium
Spongy layer of Endometrium
Perimetrium
Compact layer of Endometrium
Implantation layer of Endometrium


--Mark Hill (talk) 11:12, 4 September 2015 (AEST) 3 questions here please. I will assess after the lab today.

ANAT2341 Student 2015 Quiz Questions

Lab Assessment 5

What is the difference between Gastroschisis and Omphalocele?

Omphalocele is fetal defect (occurring 1 in every 4000 births) which is defined as the herniation of the abdominal viscera into the umbilical cord. In this abdominal wall defect, internal abdominal organs such as the intestines, liver protrude outside of the belly via the belly button where the organs are covered by a thin, opaque sac which separates the internal organs with the fluids in the amniotic sac during pregnancy. The occurrence of Omphalocele is due to the incorrect or incomplete development of the muscles of the abdominal wall.

Gastroschisis is a defect which is thought to have been caused due to the interruption of blood supply to the developing abdominal wall from the omphalomesenteric duct artery in the 8th week of gestation. Unlike Omphalocele occurring from the belly button, it is characterized by an extra-umbilical herniation of internal abdominal organs at the junction of umbilicus and normal skin (beside the belly button) and not enclosed in visceral peritoneum.

Omphalocele develops in the 9th week of development when the intestines do not re-enter the body cavity whereas Gastroschisis arises within the 6th ~ 7th week of development when the abdominal wall muscles of the baby do not develop properly


<pubmed>2932813</pubmed> <pubmed>12130917</pubmed> <pubmed>15305094</pubmed>

--Mark Hill (talk) 12:45, 7 November 2015 (AEST) (4/5)


Lab Assessment 7

1. Identify and write a brief description of the findings of a recent research paper on development of one of the endocrine organs covered in today's practical.


2. Identify the embryonic layers and tissues that contribute to the developing teeth.

Tooth development (Odontogenesis) begins in the 6th week of embryonic development and is made up of ectoderm, mesoderm and neural crest ectomesenchyme

- Ameloblasts: derived from the epithelium of ectoderm cells from the 1st pharyngeal arch which produces the enamel. Enamel covers the crown of the tooth and are only found to be present during the process of odontogenesis

- Odontoblasts: ectomesenchymal cells derived from the neural crest. These cells begin by forming the predentin which later hardens to become dentin

--Mark Hill (talk) 13:45, 7 November 2015 (AEST) Only the tooth has been described, not the endocrine development. (2/5)

Peer Reviews

Group 1

From first glance of the page, just by looking at the contents table found at the top of the wikipage, I can already see that all the sections have been planned and well thought out with the appropriate subheadings and sub-subheadings which makes the page a lot easier to navigate if I were to be searching for something in particular on the topic ‘Three Person Embryo’

The introduction is short and concise with the appropriate description of what the topic is about, adding the YouTube video in your introduction was a great touch (props to you for asking the maker permission to re-use as it’s under the YouTube Standard License) however I think this section could be improved by maybe addressing the key points that the wiki page will be covering

It’s great to see some history behind the development and progression of ‘Mitochondrial’ Donation throughout the years!! Is there any more history regarding this topic or is 1997 the first date with historical records?? Tabulation of the data may clean up this section, but otherwise great find!

Under the benefits section, no actual benefits seems to have been listed? I think this section has not yet been completed

The pictures and information under the ‘Technical Progression’ subheading is substantial and informative. The images seem to have been referenced and labelled accordingly but not sure if they are reusable as the sites / locations you obtained them from do not mention permission rights for reuse of their material. Some of the referencing done still shows the blue PMID which disrupts the flow of the project page.

It is clear that a lot of research has been done into making this page what it is currently. I would suggest firstly to check that all material used on your page is re-useable as well as fixing up the minor coding of references and also grammar and spelling mistakes throughout the page. Great work!!

Group 3

Straight away I was impressed by the images and the table of contents. It appears that all subheadings are relevant and well planned. Having the definition in the introduction was great as well as the addition of epidemiology including the map, however I think it would be much more informative for readers if you touched on the variety of topics your wikipage will be covering (if they did not bother to read the table of contents)

The variety of causes which are mentioned for Female infertility was concise and very informative under their respective sub-subheadings and with the appropriate referencing. There is a substantial amount of information provided under the ‘Pathogenesis’ section which clearly defines the different types, however, it seems that rather than Female infertility you have focused more information on ‘PCOS’ rather than all round? The images added in this heading was great in breaking up the text and the addition of animal and cell culture models were a really nice addition

The signs and symptoms section is nice and simple while giving the reader all the necessary information without lines and lines of text which makes the information easy to access however in a section of ‘Diagnosis’, I think use of paragraphing may help the reader take rests to understand the large amount of information provided in the blood testing, maybe make use of a glossary for the bolded words. Other than that the image has been reference properly and the subheadings were helpful

The tabulated information in Prevention and Treatment was a great way to avoid walls and walls of text as some of the other groups have done clearly identifying the cons of certain ‘current’ treatment methods. The amount of references that went into making this wikipage is a clear indication of how much effort was put in to making this page what it is

Great job on the project so far!! Only thing I can say is to try look for a video regarding Female infertility!! Good luck!

Group 4

I would like to say great work of find substantial information and images to go along with your wikipage. From the table of contents there seems to be a lot of topics being addressed and with your use of subheadings, it makes navigating the page much easier. The short introduction described the basic meaning of male infertility well as well as the inclusion of some basic statistics is a nice bit of information however it would be nice to have some information regarding what your wikipage will be covering in general

The background information is very useless as it provides the reader with some basic knowledge of where the male reproductive system and its components come into play in regard to the topic of male infertility. The images used are all referenced appropriately and assists in understanding where each component is located and what they look like. The tabulated data of the different types of male infertility allows the readers to easily understand the different kinds and what their relative symptoms are easily. Good job on that! The use of video is nice to see, it has relevance to your topic.

Regarding information within the section ‘Major Causes of Infertility’, the information provided is awesome, however there just seems to be too much information crammed into small paragraphs which makes it quite draining to read. There are many terms which some readers may not know or understand, so I recommend using a glossary to help sort this problem out  maybe simplify the information (if you can) or break up into more paragraphs to make it easier to read and digest. There are some sections which have no information, however I know that these will be filled by the submission date. The large amount of references is indicative of how much work went into the wikipage for your group!

Good work guys!!

Group 5

Great work so far on your wikipage guys, even just at first glance it is clear how much research and work was put in to make this page what it is. The amount of information that has been provided on the page is quite substantial. Within the contents table at the top of the page, each section has been broken down accordingly allowing ease of navigation for those who wish to know more about Oncofertility. The introduction provides us with a nice description of what Oncofertility is as well as a definition of the term ‘infertility’ which is helpful to those who do not know much information regarding the terms

I think that some information can be split up into more paragraphs, especially information in the subheading ‘Radiation’, currently it is just a wall of text which makes it extremely hard to focus and understand all the words. Seeing as it is a procedure, maybe someone can include a hand-drawn image of the process and how affects the body?

Information in the other sections are well organised and provides useful relevant information as well as providing deeper knowledge into certain techniques, chemicals and cancer cells in general. The information is a good addition (for both cancer cells and chemotherapy  however there is no referencing available to be found for both your videos. I think more images (hand-drawn or from other resources) need to be added to balance out the amount of text you have on your page.

The overall structure other than the main subheadings that you currently have could be improved as some sections are just too long and cover a too broad information to be just kept under one subheading. Make use of more dot points to summarise the information. The table under Fertility preservation in women was concise and provides easy to read data, however the colouring of the background makes it hard to distinguish where each section of the box finishes and ends (maybe I’m colour-blind). I also think that it might be helpful to add a glossary to the bottom of your wikipage as there are quite a lot of terms that people may not understand 

Overall great work on your wikipage, I look forward to reading the final version!! Good luck!

Group 6

Skimming through the page, it is clear that a lot of research has been done to make this page what it is, each subheading is well thought out (maybe a overdone a bit by the additional sub-subheadings) and allows a transition. However there is a crucial part of the page is missing, the introduction. By not having an introduction at the beginning of the page, the project just jumps straight into information giving no clues as to what the project will be covering overall. It would be nice to have a concise definition of Artificial Reproductive Technologies (maybe replace ‘ART’ for the full word for the wikipage heading) The history has some nice information, but I think it can be improved by making use of tables or a graph for each of the dates, or even dot points to break the constant text.

Overall in the other sections, the pictures are nice and are references appropriately and the use of table is nice (might be a bit dark to see the writing clearly). I think that some of the information can be broken up into small paragraphs rather than having one paragraph with around 30~40 sentences as it breaks down the information into easily digestible parts considering the amount of information which has been provided.

The advantages and disadvantages of ART have been mentioned clearly without using lots of text, it makes the information easy to understand. I also think that more images are needed considering the widespread nature of the topic you have chosen, maybe some hand drawn images for those which you cannot find copyright information or a video to explain some of the procedures. Some grammar and formatting should be done before final submission to ensure that all sections are uniform in their font and sizing.

Great work on finding all the information and making this page so far!! Good luck


--Mark Hill (talk) 13:45, 7 November 2015 (AEST) (17/20)

Lab Assessment

Cillary Body

The cillary body is the section of the eye which houses the cillary muscle, which works to control the shape of the lens, and also the cillary epithelium, which produces the aqueous humor. It is a circular thickening of the walls within the eyes which divides the vitreous body from the posterior chamber. The inner layer is transparent and continuous with the neural tissues of the retina whilst the outer layer is highly pigmented and runs continuous with the retinal pigment epithelium and forms the cells of the dilator muscle.

Embryology Link Vision - Retina Development#Retinal Pigment Epithelium

--Mark Hill (talk) 13:45, 7 November 2015 (AEST) (5/5)

References

<pubmed>26244658</pubmed> Look at this aye [2]

  1. <pubmed>25191937</pubmed>|[1]
  2. <pubmed>26244657</pubmed>

--Mark Hill (talk) 13:45, 7 November 2015 (AEST) Stem Cell Presentation (17/20)

--Mark Hill (talk) 20:42, 3 November 2015 (AEDT) CATEI submitted (5)

Test student 2015 Please do not use your real name on this website, use only your student number.

2015 Course: Week 2 Lecture 1 Lecture 2 Lab 1 | Week 3 Lecture 3 Lecture 4 Lab 2 | Week 4 Lecture 5 Lecture 6 Lab 3 | Week 5 Lecture 7 Lecture 8 Lab 4 | Week 6 Lecture 9 Lecture 10 Lab 5 | Week 7 Lecture 11 Lecture 12 Lab 6 | Week 8 Lecture 13 Lecture 14 Lab 7 | Week 9 Lecture 15 Lecture 16 Lab 8 | Week 10 Lecture 17 Lecture 18 Lab 9 | Week 11 Lecture 19 Lecture 20 Lab 10 | Week 12 Lecture 21 Lecture 22 Lab 11 | Week 13 Lecture 23 Lecture 24 Lab 12 | 2015 Projects: Three Person Embryos | Ovarian Hyper-stimulation Syndrome | Polycystic Ovarian Syndrome | Male Infertility | Oncofertility | Preimplantation Genetic Diagnosis | Students | Student Designed Quiz Questions | Moodle page

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link