Lab 4 Online Assessment
- The allantois, identified in the placental cord, is continuous with what anatomical structure?
- Identify the 3 vascular shunts, and their location, in the embryonic circulation.
- Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)
--Ashleigh Pontifex 12:55, 28 July 2011 (EST) Lab 1 Assessment
1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique.
The first In Vitro Fertilization Pre-Embryo Transfer (IVF-ET) was performed in 1978 by Dr. Edwards (an embryologist) and Dr. Steptoe in England. In 2010, Robert G. Edwards was awarded with a Nobel Prize “for the development of human in vitro fertilization (IVF) therapy”.
2. Identify a recent paper on fertilisation and describe its key findings.
Title: Enzymatic isolation of human primordial and primary ovarian follicles with Liberase DH: protocol for application in a clinical setting Authors: Julie Vanacker M.Bio.Sc.a, Alessandra Camboni M.D., Ph.D.a, Catherine Dath M.D.a, Anne Van Langendonckt Ph.D.a, Marie-Madeleine Dolmans M.D., Ph.D.a, Jacques Donnez M.D.,h.D. a, and Christiani A. Amorim V.M.D., Ph.D.a
Key findings: - The aim or objective of the experiment was to isolate human preantral follicles with a particular enzyme (Liberase Dehydrogenase) in order to use these follicles in a clinical setting. - After the follicles were isolated, they were analysed in terms of their morphology and structural preservation. - In conclusion, it was founded that Liberase DH is an extremely useful enzyme for the isolate of human preantral follicles as it helps to maintain their viability and ultrastructure. This enzyme can be produced in good manufacturing practice conditions and hence is a great contribution to clinical applications.
3. Identify 2 congenital anomalies.
Two congenital anomalies include: - Trisomy 21 (Down Syndrome): a chromosomal abnormality caused by the event of an additional copy of chromosome 21 - Cleft palate: caused by the failure of the mouth parts to join up during early foetal development which results in an open space or ‘cleft’ that can occur on one or on both sides of the face.
http://www.ivf.com/ivffaq.html http://nobelprize.org/nobel_prizes/medicine/laureates/2010/press.html http://www.sciencedirect.com.wwwproxy0.library.unsw.edu.au/science/article/pii/S0015028211008600 http://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Fertilization http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Cleft_palate_and_cleft_lip
--Ashleigh Pontifex 11:25, 29 July 2011 (EST)