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The most common side for diaphragmatic hernia is the left side because the pericardioperitoneal canal is larger than the right and closes later. Diaphragmatic is caused by a mutation in the gene that directs pulmonary development hence the left side would be more common as it seals off the pleural cavity at a later stage of development <ref>http://www.mdconsult.com.wwwproxy0.library.unsw.edu.au/books/page.do?eid=4-u1.0-B978-0-443-06811-9..10011-9--sec4&isbn=978-0-443-06811-9&uniqId=277332761-10#4-u1.0-B978-0-443-06811-9..10011-9--sec4ref>.
The most common side for diaphragmatic hernia is the left side because the pericardioperitoneal canal is larger than the right and closes later. Diaphragmatic is caused by a mutation in the gene that directs pulmonary development hence the left side would be more common as it seals off the pleural cavity at a later stage of development <ref>http://www.mdconsult.com.wwwproxy0.library.unsw.edu.au/books/page.do?eid=4-u1.0-B978-0-443-06811-9..10011-9--sec4&isbn=978-0-443-06811-9&uniqId=277332761-10#4-u1.0-B978-0-443-06811-9..10011-9--sec4ref>.




== LAB ASSESSMENT 6 ==
== LAB ASSESSMENT 6 ==


'''1. What week of development do the palatal shelves fuse?'''  
'''1. What week of development do the palatal shelves fuse?'''  

Revision as of 21:42, 14 September 2011


Lab 4 Online Assessment

  1. The allantois, identified in the placental cord, is continuous with what anatomical structure?
  2. Identify the 3 vascular shunts, and their location, in the embryonic circulation.
  3. Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)




LAB ATTENDANCE

--Z3060621 12:56, 28 July 2011 (EST)

--z3060621 12:55, 4 August 2011 (EST)

--z3060621 11:39, 11 August 2011 (EST)

--z3060621 11:18, 18 August 2011 (EST)

--z3060621 11:05, 25 August 2011 (EST)

--z3060621 11:28, 1 September 2011 (EST)

LAB ASSESSMENT 1

1. Identify the origin of In Vitro Fertilization and the 2010 nobel prize winner associated with this technique.

Robert G. Edwards, a British scientist


2. Identify a recent paper on fertilisation and describe its key findings. A recent Swedish study published in the July issue 2011 of the medical journal Pediatrics, babies conceived via In Vitro Fertilization (IVF) are more likely to get various cancers by age 19 than when naturally conceived [1].


3. Identify 2 congenital anomalies.

- Hydrocephalus - cleft palate/lip

--Mark Hill 00:38, 30 July 2011 (EST) You need to cite the reference correctly for question 2.

LAB ASSESSMENT 2

1. Identify the ZP protein that spermatozoa binds and how is this changed (altered) after fertilisation.

ZP3 is a glycoprotein sperm receptor molecule in the zona which is one of three glycoproteins composing the zona pellucida. As a result of this binding, the acrosome is induced to release degradative enzymes that allow the sperm to penetrate the zona pellucida [2].


2. Identify a review and a research article related to your group topic. (Paste on both group discussion page with signature and on your own page)

Turner's Syndrome: New England Journal of Medicine by Virginia P. Sybert, M.D., and Elizabeth McCauley, Ph.D. Issue 351 Page 1227-1238 September 16, 2004.


LAB ASSESSMENT 3

1. What is the maternal dietary requirement for late neural development?

Iodine is essential for the developing brain of the fetus [3].


2. Upload a picture relating to you group project. Add to both the Group discussion and your online assessment page. Image must be renamed appropriately, citation on "Summary" window with link to original paper and copyright information. As outlined in the Practical class tutorial.

alt text












LAB ASSESSMENT 4

1. The allantois, identified in the placental cord, is continuous with what anatomical structure?

The allantaois is continuous with the bladder [1].


2. Identify the 3 vascular shunts, and their location, in the embryonic circulation.

The three vascular shunts in the embryonic circulation include the following: ductus venosus develops within the liver, oval foramen between the atria and ductus arteriosus is the distal part of the left sixth pharyngeal arch artery passing from the left pulmonary artery to the dorsal aorta [2].


3. Identify the Group project sub-section that you will be researching. (Add to project page and your individual assessment page)

The sub-sections I will be researching in are etiology and clinical manifestation.


LAB ASSESSMENT 5

1. Which side (L/R) is most common for diaphragmatic hernia and why?

The most common side for diaphragmatic hernia is the left side because the pericardioperitoneal canal is larger than the right and closes later. Diaphragmatic is caused by a mutation in the gene that directs pulmonary development hence the left side would be more common as it seals off the pleural cavity at a later stage of development <ref>http://www.mdconsult.com.wwwproxy0.library.unsw.edu.au/books/page.do?eid=4-u1.0-B978-0-443-06811-9..10011-9--sec4&isbn=978-0-443-06811-9&uniqId=277332761-10#4-u1.0-B978-0-443-06811-9..10011-9--sec4ref>.


LAB ASSESSMENT 6

1. What week of development do the palatal shelves fuse?

at the end of the 7th week, the palatal shelves rotate rapidly upward into a horizontal position and then fuse with each other and with the primary palate to form the secondary palate

2. What animal model helped elucidate the neural crest origin and migration of cells?

Mouse mutants provide information about mechanisms of neural crest migration and developmental restrictions.


3. What abnormality results from neural crest not migrating into the cardiac outflow tract?

It causes the incomplete conotruncal septation. Ablation of cardiac neural crest cells causes persistent truncus arteriosus, tricuspid stenosis, ventricular septal defects, transposition of the great vessels, double outlet right ventricle, and tetralogy of Fallot.

REFERENCES

  1. Moore, K.L. & Persuad, T.V.N. (2008). The Developing Human: clinically oriented embryology (8th ed.). Philadelphia: Saunders.
  2. Moore, K.L. & Persuad, T.V.N. (2008). The Developing Human: clinically oriented embryology (8th ed.). Philadelphia: Saunders.