|Embryology - 26 Oct 2020 Expand to Translate|
|Google Translate - select your language from the list shown below (this will open a new external page)|
العربية | català | 中文 | 中國傳統的 | français | Deutsche | עִברִית | हिंदी | bahasa Indonesia | italiano | 日本語 | 한국어 | မြန်မာ | Pilipino | Polskie | português | ਪੰਜਾਬੀ ਦੇ | Română | русский | Español | Swahili | Svensk | ไทย | Türkçe | اردو | ייִדיש | Tiếng Việt These external translations are automated and may not be accurate. (More? About Translations)
|Educational Use Only - Embryology is an educational resource for learning concepts in embryological development, no clinical information is provided and content should not be used for any other purpose.|
Trisomy X is a caused by the presence of an extra X chromosome in females (47,XXX instead of 46,XX). This is also the most common female chromosomal abnormality, occurring in approximately 1 in 1,000 female births.
Other abnormalities of chromosome number include: female tetrasomy X (quadruple X, or 48, XXXX) a rare chromosomal disorder and male Klinefelter syndrome, the presence of an additional X chromosome (47, XXY or XXY).
- Alternative names: Triplo X syndrome, Trisomy X, 47,XXX, XXX syndrome
Some Recent Findings
|More recent papers|
This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
Search term: Trisomy X
<pubmed limit=5>Trisomy X</pubmed>
Trisomy X Karyotype
The most common prenatal diagnosis is by either amniocentesis or chorionic villi sampling.
|Feature||Estimated frequency based on current available data|
|Tall stature >75th percentile||80 - 89 %|
|Epicanthal folds||32 - 46 %|
|Clinodactyly||42 - 65 %|
|Hypotonia in infancy||55 - 71 %|
|Genitourinary malformations||5 - 16 %|
|Seizure disorder||11 - 15 %|
|Intention tremor||6 - 20 %|
|Congenital hip dysplasia||2 - 12 %|
|Constipation/Abdominal pains||12 - 45 %|
|Premature ovarian failure||unknown|
Table data from Tartaglia NR, etal., 2010
<pubmed>19732877</pubmed> <pubmed>7815443</pubmed> <pubmed>1155452</pubmed> <pubmed>14452136</pubmed>
Search Pubmed: Trisomy X
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- Genetics Home Reference triple X syndrome
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2020, October 26) Embryology Trisomy X. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Trisomy_X
- © Dr Mark Hill 2020, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G