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The dorsal bladder region bounded by the 2 ureters and the urethra form the region known as the trigone. The classical embryology description of the origin of this region was from the mesonephric duct (Wolffian duct), as shown in this animation. | The dorsal bladder region bounded by the 2 ureters and the urethra form the region known as the trigone. The classical embryology description of the origin of this region was from the mesonephric duct (Wolffian duct), as shown in this animation. | ||
More recent mouse studies suggest that this bladder region is endodermal and not mesodermal in origin.<ref name="PMID19914648"><pubmed>19914648</pubmed></ref> Using a similar mouse model, this trigone embryonic region appears to contain most of the bladder progenitor cells.<ref name="PMID24992712"><pubmed>24992712</pubmed></ref> Any mesonephric duct (Wolffian duct) | More recent mouse studies suggest that this bladder region is endodermal and not mesodermal in origin.<ref name="PMID19914648"><pubmed>19914648</pubmed></ref> Using a similar mouse model, this trigone embryonic region appears to contain most of the bladder progenitor cells.<ref name="PMID24992712"><pubmed>24992712</pubmed></ref> Any mesonephric duct (Wolffian duct) located in the mouse trigone region appears to be developmentally lost by apoptosis.<ref><pubmed>19568352</pubmed></ref> | ||
In contrast, the prostatic central zone, seminal vesicle, and ejaculatory ducts all originate from the mesonephric duct (Wolffian duct).<ref name="PMID20413145"><pubmed>20413145</pubmed></ref> | In contrast, the prostatic central zone, seminal vesicle, and ejaculatory ducts all originate from the mesonephric duct (Wolffian duct).<ref name="PMID20413145"><pubmed>20413145</pubmed></ref> |
Revision as of 13:07, 21 September 2015
Embryology - 29 Mar 2024 Expand to Translate |
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<html5media height="380" width="500">File:Trigone_001.mp4</html5media> | Development of the Trigone Region of the Urinary Bladder
The dorsal bladder region bounded by the 2 ureters and the urethra form the region known as the trigone. The classical embryology description of the origin of this region was from the mesonephric duct (Wolffian duct), as shown in this animation. More recent mouse studies suggest that this bladder region is endodermal and not mesodermal in origin.[1] Using a similar mouse model, this trigone embryonic region appears to contain most of the bladder progenitor cells.[2] Any mesonephric duct (Wolffian duct) located in the mouse trigone region appears to be developmentally lost by apoptosis.[3] In contrast, the prostatic central zone, seminal vesicle, and ejaculatory ducts all originate from the mesonephric duct (Wolffian duct).[4]
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Cite this page: Hill, M.A. (2024, March 29) Embryology Trigone Development Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Trigone_Development_Movie
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G