Testis Descent Movie

Embryology - 23 Apr 2024 Expand to Translate
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<html5media height="300" width="360">File:Testis_Descent_001.mp4</html5media>

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Testis Descent

Data from a study of male human fetal (between 10 and 35 weeks) gonad position^[1]

10 to 23 weeks - (9.45%) had migrated from the abdomen and were situated in the inguinal canal
24 to 26 weeks - (57.9%) had migrated from the abdomen
27 to 29 weeks - (16.7%) had not descended to the scrotum

mesenchymal structure occurring associated with gonad development and involved in testes descent.
Two factors - insulin-like peptide hormone 3 (INSL3) and androgen, have been shown to be involved with gubernaculum development. Insulin-like peptide 3 (INSL3) hormone receptor is RXFP20.

Human gubernaculum development: 8-12 weeks - mesonephric fold at or near the gonad; 20-25 weeks - connected to the testis or uterus.^[2]