Template talk:Australian Palate abnormalities 2002-2003

From Embryology

Cleft palate without cleft lip Description: A congenital anomaly characterised by a closure defect of the hard and/or soft palate behind the foramen incisivum without a cleft lip. This anomaly includes sub-mucous cleft palate, but excludes cleft palate with a cleft lip, a functional short palate and high narrow palate. ICD-9-BPA codes: 749.00–749.09 ICD-10-AM codes: Q35.0–Q35.9 Cleft palate without cleft lip was reported in 8.1 per 10,000 births. This overall rate has increased to 9.1 when the rate was estimated using data from the four states that include TOP data. The reported number of fetal deaths or early terminations of pregnancy with this anomaly was small and these deaths or terminations could be due to other associated anomalies. However there was an increase in the number of notified pregnancies with cleft palate without cleft lip in 2003 (Figure 15). The data from four states providing information on TOP show that the estimated rate increased from 7.7 per 10,000 pregnancies in 2002 to 10.4 per 10,000 pregnancies in 2003 (Table 2.15.2). The proportion of females with this anomaly was higher (56.9%) than males. This anomaly was seen in 52.7 per 10,000 babies born before 25 weeks of gestation. Of the babies who had this anomaly 83.0% were born at term and most of the babies (82.7%) had a birthweight of 2,500 grams or more (Table 2.15.3). Women aged 40 years or older and women born in South Central America or the Caribbean region had the highest rates of affected births. Multiple births had a significantly higher rate of affected babies than singleton births (PR=1.9, CI 1.1–3.3). The rates did not differ significantly by Indigenous status or areas of residence (Table 2.15.6).

Cleft lip with or without cleft palate Description: A congenital anomaly characterised by a partial or complete clefting of the upper lip, with or without clefting of the alveolar ridge or the hard palate. Excludes a midline cleft of the upper or lower lip and an oblique facial fissure (going towards the eye). ICD-9-BPA codes: 749.10–749.19, 749.20–749.29 ICD-10-AM codes: Q36.0, Q36.1, Q36.9, Q37.0–Q37.5, Q37.8, Q37.9 There were 9.2 per 10,000 births with cleft lip with or without cleft palate reported during the period 2002–2003 (Table 2.16.1) and this rate was steady over the six year period, 1998–2003 (Figure 16, Table 2.16.2). About 17% of the affected pregnancies were terminated in early pregnancy or resulted in fetal deaths. Most of the fetal deaths or terminations of pregnancy (95%) had multiple abnormalities. This anomaly was more commonly seen in males than in females. Among the babies born before 25 weeks of gestation, 150 per 10,000 births had this anomaly. Most babies (80.0%) were born at term with a birthweight of 2,500 grams or more (Table 2.16.3). Maternal age group was not associated with the anomaly. The rate of births with the anomaly was significantly higher among Indigenous women than non Indigenous women (PR=1.6, CI 1.01–2.4). The areas of residence, parity or plurality were not significantly different in these women (Table 2.16.6). Figure 16: Rate of cleft lip with or without cleft palate among all births(a) and estimated rate(b), 1998–2003