Template:Week 8 Embryo Stages and Events table: Difference between revisions

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| '''Event'''
| '''Event'''
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| <center>43</center>
| <center>50</center>
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| [[Carnegie stage 20|Stage 20]]
| [[Endocrine - Pancreas Development]] Week 7 to 20 pancreatic hormones secretion increases, small amount maternal insulin
| [[File:Stage20_bf1c.jpg|200px|link=Carnegie stage 20]]
 
[[Head Development|Head]]  scalp vascular plexus visible


[[Respiratory System Development]]  Week 7 - enlargement of liver stops descent of heart and lungs
[[Musculoskeletal_System_-_Limb_Development|Limb]]  upper limbs begin to rotate ventrally


|-
[[Neural_System_Development|Neural]] - amygdaloid body has at least four individual nuclei<ref><pubmed>2268071</pubmed></ref>
| <center>44</center>
| [[Carnegie_stage_18|Stage 18]]
| [[File:Stage18_bf1c.jpg|200px|link=Carnegie stage 18]]


[[Musculoskeletal_System_-_Limb_Development|Limb]]  [[Musculoskeletal_System_-_Bone_Development|Bone]] form by endochondrial ossification and throughout embryo replacement of cartilage with bone (week 5-12).
oculomotor nerve shows a dorsolateral and a ventromedial portion


[[Sensory_-_Smell_Development|Smell]]  vomeronasal fibres and nervus terminalis <ref name=PMID15604533><pubmed>15604533</pubmed></ref>
rhombic lip (rhombencephalon) formation of the cerebellum (intermediate layer) and of the cochlear nuclei


[[Gastrointestinal_Tract_-_Liver_Development|Liver]]  obturation due to epithelial proliferation, bile ducts became reorganized, continuity between liver cells and gut <ref name=PMID9407542><pubmed>9407542</pubmed></ref>
cerebellum cell layer (future Purkinje cells) develops


[[Neural System Development]]  duramater appears <ref name=PMID15478101><pubmed>15478101</pubmed></ref>
choroid plexuses of the fourth and lateral ventricles
 
|-bgcolor="FAF5FF"
| <center>51</center>
| &nbsp;
| [[Gastrointestinal Tract Development|Gastrointestinal Tract]] anal (cloacal) membrane perforates


|-
|-
| <center>45</center>
| <center>52</center>
| &nbsp;
| [[Carnegie stage 21|Stage 21]]
| &nbsp;
| [[File:Stage21_bf1c.jpg|200px|link=Carnegie stage 21]]
 
[[Neural_System_Development|Neural]] - cortical plate appears in the area of future insula<ref name="PMID2252222"><pubmed>2252222</pubmed></ref>
 
[[Musculoskeletal_System_-_Limb_Development|Limb]]  upper and lower limbs rotate


[[Gastrointestinal_Tract_-_Liver_Development|Liver]] (stage 18 to 23) biliary ductules developed in periportal connective tissue produces ductal plates that receive biliary capillaries <ref name=PMID9407542><pubmed>9407542</pubmed></ref>
[[Coelomic Cavity Development|Intraembryonic Coelom]]  pericardioperitoneal canals close


|-
|-bgcolor="FAF5FF"
| <center>46</center>
| <center>53</center>
| &nbsp;
| &nbsp;
| &nbsp;
| &nbsp;


|-
|-
| <center>47</center>
| <center>54</center>
| &nbsp;
| [[Carnegie stage 22|Stage 22]] 
| &nbsp;
| [[File:Stage22_bf1c.jpg|200px|link=Carnegie stage 22]][[Neural_System_Development|Neural]] - neocortical fibres project to epithalamus, to dorsal thalamus, and to mesencephalon<ref name="PMID2252222" />
 
[[Musculoskeletal_System_-_Limb_Development|Limb]]  fingers and toes lengthen
 
[[Sensory_-_Smell_Development|Sense - Smell]]  Stage 22 to early fetal period - migratory streams of neurons from the subventricular zone of the olfactory bulb towards the future claustrum<ref name="PMID15604533"><pubmed>15604533</pubmed></ref>
 
|-bgcolor="FAF5FF"
| <center>55</center>
|
| [[Genital System Development|Genital]]  8 Weeks  Testis - mesenchyme, interstitial cells (of Leydig) secrete testosterone, androstenedione
 
[[Genital System Development|Genital]] 8 to 12 Weeks - hCG stimulates testosterone production
 
[[Tongue_Development|Tongue]]  Week 8 - nerves penetrate epitheilai basal lamina and synapse with undifferentiated, elongated, epithelial cells (taste bud progenitor cell)


|-
|-
| <center>48</center>
| <center>56</center>
| [[Carnegie_stage_19|Stage 19]]
| [[Carnegie stage 23|Stage 23]]
| [[File:Stage19_bf1c.jpg|200px|link=Carnegie stage 19]] [[Neural System Development]]  accessory olivary nucleus appears<ref name=PMID2268071><pubmed>2268071</pubmed></ref>
| [[File:Stage23_bf1c.jpg|200px|link=Carnegie stage 23]] [[Carnegie stage 23|Stage 23]] defines the end of the embryonic (organogenesis) period
 
'''Mesoderm ''' heart prominence, ossification continues
 
[[Head Development|Head]]  nose, eye, external acoustic meatus, eyelids, external ears, rounded head
 
'''Body '''- straightening of trunk, heart, liver, umbilical cord, intestines herniated at umbilicus
 
[[Musculoskeletal_System_-_Limb_Development|Limb]]  upper limbs longer and bent at elbow, hands and feet turned inward, foot with separated digits, wrist, hand with separated digits
 
'''Extraembryonic Coelom'''  chorionic cavity is now lost by fusion with the expanding amniotic cavity
 
[[Neural_System_Development|Neural]] - rhombencephalon, pyramidal decussation present, nuclei and tracts similar to those present in the newborn cerebellum present as only a plate connected to midbrain and hindbrain through fibre bundles<ref name="PMID2244584"><pubmed>2244584</pubmed></ref>


|-
[[Musculoskeletal_System_-_Axial_Skeleton_Development|Axial Skeleton]] vertebral column 33 or 34 cartilaginous vertebrae (20-33 mm in total length), vertebral pedicles, articular and transverse processes identifiable (no spinous processes)<ref name="PMID7216919"><pubmed>7216919</pubmed></ref>
| <center>49</center>
 
| &nbsp;
|-bgcolor="FAF5FF"
| &nbsp;
| <center>&nbsp;</center>
| Week 8
| [[Gastrointestinal_Tract_-_Stomach_Development|Stomach]] - Week 8 - Gastrin containing cells in stomach antrum. Somatostatin cells in both the antrum and the fundus.
|-
|-
| colspan=3|Note - the day timing of stages is only approximate, system names link to first page of that specific system, and events are based upon the literature cited below.
| colspan=3|Note - the day timing of stages is only approximate, system names link to first page of that specific system, and events are based upon the literature cited below.

Revision as of 14:58, 5 April 2016

Week 8 - Human Embryo Stages and Events (GA week 10) 
Embryo Week: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9
Day
Stage
Event
50
Stage 20 Stage20 bf1c.jpg

Head scalp vascular plexus visible

Limb upper limbs begin to rotate ventrally

Neural - amygdaloid body has at least four individual nuclei[1]

oculomotor nerve shows a dorsolateral and a ventromedial portion

rhombic lip (rhombencephalon) formation of the cerebellum (intermediate layer) and of the cochlear nuclei

cerebellum cell layer (future Purkinje cells) develops

choroid plexuses of the fourth and lateral ventricles

51
  Gastrointestinal Tract anal (cloacal) membrane perforates
52
Stage 21 Stage21 bf1c.jpg

Neural - cortical plate appears in the area of future insula[2]

Limb upper and lower limbs rotate

Intraembryonic Coelom pericardioperitoneal canals close

53
   
54
Stage 22 Stage22 bf1c.jpgNeural - neocortical fibres project to epithalamus, to dorsal thalamus, and to mesencephalon[2]

Limb fingers and toes lengthen

Sense - Smell Stage 22 to early fetal period - migratory streams of neurons from the subventricular zone of the olfactory bulb towards the future claustrum[3]

55
Genital 8 Weeks Testis - mesenchyme, interstitial cells (of Leydig) secrete testosterone, androstenedione

Genital 8 to 12 Weeks - hCG stimulates testosterone production

Tongue Week 8 - nerves penetrate epitheilai basal lamina and synapse with undifferentiated, elongated, epithelial cells (taste bud progenitor cell)

56
Stage 23 Stage23 bf1c.jpg Stage 23 defines the end of the embryonic (organogenesis) period

Mesoderm heart prominence, ossification continues

Head nose, eye, external acoustic meatus, eyelids, external ears, rounded head

Body - straightening of trunk, heart, liver, umbilical cord, intestines herniated at umbilicus

Limb upper limbs longer and bent at elbow, hands and feet turned inward, foot with separated digits, wrist, hand with separated digits

Extraembryonic Coelom chorionic cavity is now lost by fusion with the expanding amniotic cavity

Neural - rhombencephalon, pyramidal decussation present, nuclei and tracts similar to those present in the newborn cerebellum present as only a plate connected to midbrain and hindbrain through fibre bundles[4]

Axial Skeleton vertebral column 33 or 34 cartilaginous vertebrae (20-33 mm in total length), vertebral pedicles, articular and transverse processes identifiable (no spinous processes)[5]

 
Week 8 Stomach - Week 8 - Gastrin containing cells in stomach antrum. Somatostatin cells in both the antrum and the fundus.
Note - the day timing of stages is only approximate, system names link to first page of that specific system, and events are based upon the literature cited below.
References
  1. <pubmed>2268071</pubmed>
  2. 2.0 2.1 <pubmed>2252222</pubmed>
  3. <pubmed>15604533</pubmed>
  4. <pubmed>2244584</pubmed>
  5. <pubmed>7216919</pubmed>