Template:Valproic Acid Teratogenic Dose table

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Species Difference for Teratogenic Dose (lowest) mg/kg/day
Species	Neural tube defects	Skeletal defects	Route
Man	30	20-30	Oral
Monkey	not observed	150	oral
Rabbit	not observed	150	oral
Rat	not observed	150	oral
Hamster	300	not investigated	ip
Mouse	200	200, 250, 400	ip, sc, oral
Table Data^[1] Links: drugs

↑ Nau H. (1986). Species differences in pharmacokinetics and drug teratogenesis. Environ. Health Perspect. , 70, 113-29. PMID: 3104022

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