Template:Spleen Timeline Table: Difference between revisions
From Embryology
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| marginal zone appears in reticular framework around the white pulp.<br> | | marginal zone appears in reticular framework around the white pulp.<br> | ||
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| colspan=3|Human embryonic data{{#pmid:25403423|PMID25403423}} and fetal data {{#pmid:19255788|PMID19255788}} Links: {{spleen}} | [[Kyoto Collection]] | | | colspan=3|Human embryonic data{{#pmid:25403423|PMID25403423}} and fetal data {{#pmid:19255788|PMID19255788}} Links: {{spleen}} | [[Kyoto Collection]] | {{timeline}} | ||
|}<noinclude>[[Category:Spleen]][[Category:Human]][[Category:Timeline]][[Category:Template]][[Category:Table]][[Category:Fetal]]</noinclude> | |}<noinclude>[[Category:Spleen]][[Category:Human]][[Category:Timeline]][[Category:Template]][[Category:Table]][[Category:Fetal]]</noinclude> |
Revision as of 13:17, 12 February 2019
Feature | ||
---|---|---|
Carnegie stage 14 to 17
appears as a bulge in the dorsal mesogastrium. Mesothelium pseudostratified. | ||
Mesothelium (pseudostratified} replaced with high columnar cells and then low columnar cells. | ||
Basement membrane present after this stage. | ||
Hematopoietic cells detected. | ||
Spleen is now apparent. Mesenchymal cells differentiated from cells in dorsal mesogastrium. Sinus and hilus formation after this stage. | ||
Arteries and veins parallel entries at this stage. | ||
Feature | ||
reticulum cells (alpha-smooth muscle actin-positive) scattered around the arterioles | ||
reticulum cells increase in number and began to form a reticular framework. Accumulation of T and B lymphocytes within this framework, and a primitive white pulp was observed around the arterioles. | ||
reticular framework antigenic diversity, and T and B lymphocytes were segregated in the framework. T lymphocytes were sorted into the alpha-SMA-positive reticular framework, and the periarteriolar lymphoid sheath (PALS) was formed around the arteriole. B lymphocytes aggregated in eccentric portions to the PALS and formed the lymph follicle (LF, reticular framework alpha-SMA-negative). | ||
marginal zone appears in reticular framework around the white pulp. | ||
Human embryonic data[1] and fetal data [2] Links: spleen | Kyoto Collection | timeline |
- ↑ Endo A, Ueno S, Yamada S, Uwabe C & Takakuwa T. (2015). Morphogenesis of the spleen during the human embryonic period. Anat Rec (Hoboken) , 298, 820-6. PMID: 25403423 DOI.
- ↑ Satoh T, Sakurai E, Tada H & Masuda T. (2009). Ontogeny of reticular framework of white pulp and marginal zone in human spleen: immunohistochemical studies of fetal spleens from the 17th to 40th week of gestation. Cell Tissue Res. , 336, 287-97. PMID: 19255788 DOI.