Template:Papanicolaou1933 guinea pig and rat vaginal smear table

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Vaginal Smear Comparison Table
Guinea pig	Rat (Long and Evans)
I. Superﬁcial squamous cells with pyknotic nuclei; progressive leucopenia.	1. Small round nucleated cells; disappearance of leucocytes.
Intermediate (cornification) period a. Many corniﬁed cells, usually mixed with type I cells; b. Prevalence of corniﬁed cells with cheesy masses; leucopenia	Cornification period 2. Early corniﬁed cell stage; leucocytes scarce. 3. Late corniﬁed cell stage with large cheesy masses; leucopenia
II, III, IV. Appearance of deep layer cells; reappearance and great exodus of leucocytes; gradual disappearance of corniﬁecl cells; sometimes erythrocytes present.	4. Leucocytic-corniﬁed cell stage; reappearance of leucocytes; gradual disappearance of the corniﬁed cells.
V. Dioestrus: Leucocytes and atypical atypical vaginal cells.	5. Dioestrus: Leucocytes and vaginal cclls.
Reference: Papanicolaou GN. The Sexual Cycle in the Human Female as revealed by Vaginal Smears. Am J Anat. 1933;52: 519–637. Links: Estrous Cycle \| Guinea Pig Development \| Rat Development