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From Embryology
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* '''0 Days'''   
* '''Day 0'''  One Cell Egg


:* Fertilisation
* '''Day 1'''  Dividing cells. Cleavage of cells has begun. Day ends with 4 cells present


* '''1 Day'''   
* '''Day 2'''  Formation of Morula


:* Cleavage of cells has begun. Day ends with 4 cells present
* '''Day 3'''    Advanced Segmentation. 16-25 cells within same sized morula.  


* '''2 Days'''  
* '''Day 4'''   Blastocyst formation


:* Formation of Morula
* '''Day 4 ½'''  Implantation and invasion into the uterine epithelium


* '''3 Days'''  
* '''Day 5'''   Embryoblast and trophoblast formation.


:* Compaction of morula. 16-25 cells within same sized morula.
* '''Day 6'''  Differentiation of Egg Cylinder


* '''4 Days'''   
* '''Days 6 ½'''  Advanced Endodermal Reaction


:* Blastocyst formation
* '''Day 7'''  Amnion formation


* '''4.5 Days'''   
* '''Day 7 ½'''  Neural Plate, Presomite Stage


:* Implantation and invasion into the uterine epithelium
* '''Day 8'''  First somite formation. Day ends with 1 - 7 somites present


* '''5 Days'''   
* '''Day 8 ½'''   Rotation of the Embryo. 8 - 12 somites present    


:* Embryoblast and trophoblast formation.  
* '''Day 9'''  Formation and Closure of the anterior neuropore. 13 - 20 somites present in the embryo


:* Endometrial reaction occurs
* '''Day 9 ½ '''  Formation of the posterior neuropore and forelimb bud. There are 21 - 29 somites present. The embryo is 1.8 - 3.3 mm. 


* '''6 Days'''   
* '''Day 10'''  Closure of the posterior neuropore and hind limb bud and tail bud formation occurs. 30-34 somites present and the embryo is 3.1-3.9mm.


:* Embryoblast begins to divide into embryonic and extramembryonic cavities.  
* '''Day 10 ½'''  Deep lens indentation occurs. There are 35-30 somites present and the embryo is now 3.5-4.9mm.  


:* The proamniotic cavity also starts to form.  
* '''Day 11'''  The lens vesicle closes. There are 40-44 somites present and the embryo has reached 5-6mm in length.  


:* Trophoblast cells also begin to differentiate
* '''Day 11 ½'''  The lens vesicle is now completely spearated from the surface of the embryo. There are currently 45 - 47 somites and the embryo reaches a length of 6 - 7mm


* '''6.5 Days'''   
* '''Day 12'''  Features the earliest signs of fingers forming. The embryo is 7 - 9mm in length from crown to rump and there are 48 - 51 somites.


:* Axis of embryonic germ disc is defined.  
* '''Day 13'''  The footplate becomes indented with the early toe structures. The pinna (external ear) development occurs rapidly. The embryo is now 9 - 11mm in length and has 52 - 55 somites.  


:* Uterine reaction (decidual reaction) occurs.  
* '''Day 14'''  The fingers begin to separate distally. The embryo has 56 - 66 somites and is 11-12mm in length. 


* '''7 Days'''   
* '''Day 15'''  The toes separate. at this stage, the embryo is 12 - 144m from crown to rump.


:* Formulation of amnion occurs.  
* '''Day 16'''  The umbilical hernia is repositioned. The fetus now measures between 14 and 17 mm.


:* Formation of mesoderm, entoderm and endometrium also occur.  
* '''Day 17'''  The Fingers and Toes align and join together. The skin is wrinkled and thickened and the umbilical hernia has disappeared. The fetus measures 16.5 - 20mm depending on the degree of curvature.  


* '''7 ½ Days'''   
* '''Day 18'''   The whiskers have increased in length dramatically. The length of the embryo varies between 18 and 23 mm due to the degree of curvature of the fetus.    


:* Closure of the amnion.
* '''Day 19'''  The Newborn mouse is between 23 and 27 mm due to varying degrees of flexure of the body axis.
 
:* The neural plate is clearly delimited anteriorly and laterally.
 
:* The head process is now developing.
 
:* Foregut development begins.
 
:* Blood islands develop in the wall of the yolk sac.
 
* '''8 Days''' 
 
:* Embryo has 1-7 somites present.
 
:* Progressive deepening of the neural tube. 
 
:* Circulatory system development begins.
 
:* Intestinal tract development continues.
 
:* Central nervous system development begins.
 
:* Extraembryonic membranes grow and begin to fuse.
 
:* Yolk sac continues to enlarge.
 
* '''8 ½ Days''' 
 
:* 8-12 somites present. 
 
:* rotation of embryo occurs.
 
:* development of the systems continues 
 
* '''9 Days'''   
 
:* 13-20 somites present.
 
:* Turning of the embryo has completed.
 
:* Central nervous system circulatory system and intestinal tract development continues.
 
:* The urogenital system development begins.
 
:* Placenta development begins.
 
* '''9 ½ Days''' 
 
:* 21-29 somites present. The embryo is 1.8-3.3 mm.
 
:* Cardiovascular, CNS, Intestinal and urogenital development continue.
 
:* Condensation of forelimb bud occurs.
 
* '''10 days'''
 
:* 30-34 somites present. The embryo is 3.1-3.9mm.
 
:* Systemic development continues.
 
:* The lens plate is slightly indented and the olfactory placode is visibly indented.
 
:* The posterior neuropore is beginning to close.
 
:* Placental development continues.
 
:* Hind limb bud and Tail limb bud formation occurs.
 
* '''10 ½ days'''
 
:* 35-30 somites present and the embryo is now 3.5-4.9mm.
 
:* Development of the systems continues .
 
:* Appendages and tail are developing rapidly.
 
:* Olfactory discs are more developed, with a noticeable marginal lip forming. 
 
:* The lens vesicles are also progressing in development. 
 
* '''11 Days'''
 
:* 40-44 somites present and the embryo has reached 5-6mm in length.
 
:* Closure of the lens vesicle occurs. Systemic development continues. 
 
:* Vertebral column development begins.
 
* '''11 ½ Days'''
 
:* over 45 somites present and the length of the embryo has reached 6-7mm.
 
:* external features are becoming more defined.
 
:* Systemic development is progressing.
 
:* Limb development is continuing.
 
* '''12 Days'''
 
:* the embryo is now 7-9mm in length measured from crown to rump.
 
:* Development of fingers begins.
 
:* Development of all systems continues. 
 
* '''13 days'''
 
:* the embryo is 9-11mm in length.
 
:* External features continue to grow whiskers and hair follicle have begun to form.
 
:* The handplate is indented and the footplate is starting to indent.
 
:* Systemic development continues as skeletal system development commences.

Revision as of 21:00, 13 September 2009

  • Day 0 One Cell Egg
  • Day 1 Dividing cells. Cleavage of cells has begun. Day ends with 4 cells present
  • Day 2 Formation of Morula
  • Day 3 Advanced Segmentation. 16-25 cells within same sized morula.
  • Day 4 Blastocyst formation
  • Day 4 ½ Implantation and invasion into the uterine epithelium
  • Day 5 Embryoblast and trophoblast formation.
  • Day 6 Differentiation of Egg Cylinder
  • Days 6 ½ Advanced Endodermal Reaction
  • Day 7 Amnion formation
  • Day 7 ½ Neural Plate, Presomite Stage
  • Day 8 First somite formation. Day ends with 1 - 7 somites present
  • Day 8 ½ Rotation of the Embryo. 8 - 12 somites present
  • Day 9 Formation and Closure of the anterior neuropore. 13 - 20 somites present in the embryo
  • Day 9 ½ Formation of the posterior neuropore and forelimb bud. There are 21 - 29 somites present. The embryo is 1.8 - 3.3 mm.
  • Day 10 Closure of the posterior neuropore and hind limb bud and tail bud formation occurs. 30-34 somites present and the embryo is 3.1-3.9mm.
  • Day 10 ½ Deep lens indentation occurs. There are 35-30 somites present and the embryo is now 3.5-4.9mm.
  • Day 11 The lens vesicle closes. There are 40-44 somites present and the embryo has reached 5-6mm in length.
  • Day 11 ½ The lens vesicle is now completely spearated from the surface of the embryo. There are currently 45 - 47 somites and the embryo reaches a length of 6 - 7mm
  • Day 12 Features the earliest signs of fingers forming. The embryo is 7 - 9mm in length from crown to rump and there are 48 - 51 somites.
  • Day 13 The footplate becomes indented with the early toe structures. The pinna (external ear) development occurs rapidly. The embryo is now 9 - 11mm in length and has 52 - 55 somites.
  • Day 14 The fingers begin to separate distally. The embryo has 56 - 66 somites and is 11-12mm in length.
  • Day 15 The toes separate. at this stage, the embryo is 12 - 144m from crown to rump.
  • Day 16 The umbilical hernia is repositioned. The fetus now measures between 14 and 17 mm.
  • Day 17 The Fingers and Toes align and join together. The skin is wrinkled and thickened and the umbilical hernia has disappeared. The fetus measures 16.5 - 20mm depending on the degree of curvature.
  • Day 18 The whiskers have increased in length dramatically. The length of the embryo varies between 18 and 23 mm due to the degree of curvature of the fetus.
  • Day 19 The Newborn mouse is between 23 and 27 mm due to varying degrees of flexure of the body axis.