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From Embryology
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Approximate Timing of Early Human Events (in vitro) | ||||
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10 min - components | 29 min - spermatozoa penetrates zone pellucida | 31 min - spermatozoa penetrates oocyte - fertilization | 4 hr - second polar body | 8 hr - pronuclei |
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19 hr 35 min - pronuclei fusion | 22 hr - first mitosis | 23 hr - two blastomeres | 35 hr - second mitosis | 37 hr - four blastomeres |
See also clock in lower righthand corner for the approximate timing of events. | ||||
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Reference: PMID 22695746 J Assist Reprod Genet. |