Template:CAH table collapse: Difference between revisions
From Embryology
(Created page with "{| class="wikitable mw-collapsible mw-collapsed" ! colspan=4|Congenital Adrenal Hyperplasia |-bgcolor="CEDFF2" ! width=180px|Type ! width=300px|Enzyme Deficiency ! Female ! Ma...") |
mNo edit summary |
||
(4 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
{| class="wikitable mw-collapsible mw-collapsed" | {| class="wikitable mw-collapsible mw-collapsed" | ||
! colspan=4|Congenital Adrenal Hyperplasia | ! colspan=4|Congenital Adrenal Hyperplasia | ||
|-bgcolor="CEDFF2" | |-bgcolor="CEDFF2" | ||
! width=180px|Type | ! width=180px|Type | ||
Line 9: | Line 9: | ||
| classic virilizing adrenal hyperplasia | | classic virilizing adrenal hyperplasia | ||
| 21-hydroxylase, 11-beta-hydroxylase,<br>or 3-beta-hydroxysteroid dehydrogenase | | 21-hydroxylase, 11-beta-hydroxylase,<br>or 3-beta-hydroxysteroid dehydrogenase | ||
| ambiguous genitalia at birth - complete or partial fusion of the labioscrotal folds and a phallic urethra to clitoromegaly, partial fusion of the labioscrotal folds, or both | | ambiguous genitalia at birth - complete or partial fusion of the labioscrotal folds and a phallic urethra to clitoral enlargement (clitoromegaly), partial fusion of the labioscrotal folds, or both | ||
| normal genitalia, present at age 1-4 weeks with salt wasting (salt-wasting adrenal hyperplasia) | | normal genitalia, present at age 1-4 weeks with salt wasting (salt-wasting adrenal hyperplasia) | ||
|-bgcolor="F5FAFF" | |-bgcolor="F5FAFF" | ||
| simple virilizing adrenal hyperplasia | | simple virilizing adrenal hyperplasia | ||
| mild 21-hydroxylase | | mild 21-hydroxylase | ||
| identified later in childhood because of precocious pubic hair, clitoromegaly, or both, often accompanied by accelerated growth and skeletal maturation | | identified later in childhood because of precocious pubic hair, clitoral enlargement (clitoromegaly), or both, often accompanied by accelerated growth and skeletal maturation | ||
| early genital development (pubic hair and/or phallic enlargement) accelerated growth and skeletal maturation | | early genital development (pubic hair and/or phallic enlargement) accelerated growth and skeletal maturation | ||
|- | |- | ||
Line 20: | Line 20: | ||
| milder deficiencies of 21-hydroxylase<br>or 3-beta-hydroxysteroid dehydrogenase | | milder deficiencies of 21-hydroxylase<br>or 3-beta-hydroxysteroid dehydrogenase | ||
| present at puberty or adult with infrequent menstruation (oligomenorrhea), abnormal hair growth (hirsutism), and/or infertility | | present at puberty or adult with infrequent menstruation (oligomenorrhea), abnormal hair growth (hirsutism), and/or infertility | ||
| | |||
|-bgcolor="F5FAFF" | |-bgcolor="F5FAFF" | ||
| 17-hydroxylase deficiency syndrome | | 17-hydroxylase deficiency syndrome | ||
Line 27: | Line 28: | ||
| steroidogenic acute regulatory (StAR) deficiency have ambiguous genitalia or female genitalia, at puberty may lack breast development and may have hypertension | | steroidogenic acute regulatory (StAR) deficiency have ambiguous genitalia or female genitalia, at puberty may lack breast development and may have hypertension | ||
|- | |- | ||
| colspan=4|This is a complex steroidogenic abnormality, and the above table of clinical descriptions are provided only a guide. | | colspan=4|<center>This is a complex steroidogenic abnormality, and the above table of clinical descriptions are provided only a guide.</center> | ||
|- | |||
:'''Links:''' [[Genital_System_-_Abnormalities#Congenital_Adrenal_Hyperplasia|Genital Abnormalities]] | [[Endocrine - Adrenal Development|Adrenal Development]] | | colspan=4| | ||
:'''Links:''' [[Genital_System_-_Abnormalities#Congenital_Adrenal_Hyperplasia|Genital Abnormalities]] | [[Endocrine - Adrenal Development|Adrenal Development]] | [http://www.ncbi.nlm.nih.gov/books/NBK22173/ Genes and Disease] | [http://omim.org/entry/201910 OMIM 21 Deficiency] | [http://omim.org/entry/202110 OMIM 17 Deficiency] | [http://omim.org/entry/201810 OMIM 3 Deficiency] | |||
|}<noinclude>[[Category:Template]][[Category:Adrenal]][[Category:Endocrine]][[Category:Abnormal Development]]</noinclude> | |}<noinclude>[[Category:Template]][[Category:Adrenal]][[Category:Endocrine]][[Category:Abnormal Development]]</noinclude> |
Latest revision as of 10:47, 2 June 2016
Congenital Adrenal Hyperplasia | |||
---|---|---|---|
Type | Enzyme Deficiency | Female | Male |
classic virilizing adrenal hyperplasia | 21-hydroxylase, 11-beta-hydroxylase, or 3-beta-hydroxysteroid dehydrogenase |
ambiguous genitalia at birth - complete or partial fusion of the labioscrotal folds and a phallic urethra to clitoral enlargement (clitoromegaly), partial fusion of the labioscrotal folds, or both | normal genitalia, present at age 1-4 weeks with salt wasting (salt-wasting adrenal hyperplasia) |
simple virilizing adrenal hyperplasia | mild 21-hydroxylase | identified later in childhood because of precocious pubic hair, clitoral enlargement (clitoromegaly), or both, often accompanied by accelerated growth and skeletal maturation | early genital development (pubic hair and/or phallic enlargement) accelerated growth and skeletal maturation |
nonclassic adrenal hyperplasia | milder deficiencies of 21-hydroxylase or 3-beta-hydroxysteroid dehydrogenase |
present at puberty or adult with infrequent menstruation (oligomenorrhea), abnormal hair growth (hirsutism), and/or infertility | |
17-hydroxylase deficiency syndrome | 17-hydroxylase deficiency or 3-beta-hydroxysteroid dehydrogenase |
rare, phenotypically female at birth do not develop breasts or menstruate in adolescence and may have hypertension | steroidogenic acute regulatory (StAR) deficiency have ambiguous genitalia or female genitalia, at puberty may lack breast development and may have hypertension |