Template:Blastocyst Hippo table

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Mouse Blastocyst (32 cell stage) Fate
Inner cells	Outer cells
Angiomotin (Amot) phosphorylation at adherens junctions	Amot sequestered by cell polarization from basolateral adherens junctions
Hippo active	Hippo inactive
Notch inactive	Notch active
Cdx2 not expressed	Cdx2 expressed
ICM - inner cell mass fate	TE - trophectoderm fate
Hippo^[1](TEAD4) and Notch^[2](Cdx2) together appear regulate early blastocyst fate development.

↑ Sasaki H. (2015). Position- and polarity-dependent Hippo signaling regulates cell fates in preimplantation mouse embryos. Semin. Cell Dev. Biol. , 47-48, 80-7. PMID: 25986053 DOI.
↑ Rayon T, Menchero S, Nieto A, Xenopoulos P, Crespo M, Cockburn K, Cañon S, Sasaki H, Hadjantonakis AK, de la Pompa JL, Rossant J & Manzanares M. (2014). Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Dev. Cell , 30, 410-22. PMID: 25127056 DOI.

[PMID25986053-1] Sasaki H. (2015). Position- and polarity-dependent Hippo signaling regulates cell fates in preimplantation mouse embryos. Semin. Cell Dev. Biol. , 47-48, 80-7. PMID: 25986053 DOI.

[PMID25127056-2] Rayon T, Menchero S, Nieto A, Xenopoulos P, Crespo M, Cockburn K, Cañon S, Sasaki H, Hadjantonakis AK, de la Pompa JL, Rossant J & Manzanares M. (2014). Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Dev. Cell , 30, 410-22. PMID: 25127056 DOI.

[1]

[2]